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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45B
All Species:
41.82
Human Site:
Y133
Identified Species:
92
UniProt:
Q96B21
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B21
NP_620143.1
275
31826
Y133
F
M
E
G
F
L
F
Y
Y
H
V
H
N
R
P
Chimpanzee
Pan troglodytes
XP_001151660
275
31822
Y133
F
M
E
G
F
L
F
Y
Y
H
V
H
N
R
P
Rhesus Macaque
Macaca mulatta
XP_001111835
573
63247
Y431
F
M
E
G
F
L
F
Y
Y
H
V
H
N
R
P
Dog
Lupus familis
XP_536531
532
59743
Y391
F
T
E
G
F
L
F
Y
Y
H
V
H
N
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ2
278
32370
Y136
F
I
E
G
F
L
F
Y
F
H
V
H
N
R
P
Rat
Rattus norvegicus
Q497B2
278
32319
Y136
F
V
E
G
F
L
F
Y
F
H
V
H
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506350
563
61793
Y321
F
T
E
G
F
L
F
Y
Y
H
V
H
N
R
P
Chicken
Gallus gallus
XP_417866
281
32113
Y137
F
V
E
G
C
L
F
Y
Y
H
V
L
H
R
P
Frog
Xenopus laevis
Q6NS09
280
31983
Y137
I
V
E
G
L
L
F
Y
Y
H
V
H
N
R
P
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
Y140
F
V
E
G
F
L
F
Y
F
H
I
H
N
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
Y137
A
V
E
G
F
L
F
Y
Y
H
T
H
G
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
45.7
42.8
N.A.
79.1
76.9
N.A.
32.1
58.3
62.8
53.7
N.A.
N.A.
N.A.
N.A.
33.8
Protein Similarity:
100
100
46.9
47.3
N.A.
88.4
85.9
N.A.
39.9
75
77.1
71.3
N.A.
N.A.
N.A.
N.A.
55.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
93.3
73.3
80
73.3
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
86.6
86.6
93.3
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
82
0
0
0
82
0
100
0
28
0
0
0
0
0
0
% F
% Gly:
0
0
0
100
0
0
0
0
0
0
0
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
100
0
91
10
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
100
0
0
0
0
0
10
0
0
0
% L
% Met:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
46
0
0
0
0
0
0
0
0
82
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
73
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _