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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45B
All Species:
11.52
Human Site:
Y41
Identified Species:
25.33
UniProt:
Q96B21
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B21
NP_620143.1
275
31826
Y41
R
K
N
S
P
L
H
Y
Y
Q
R
L
E
I
V
Chimpanzee
Pan troglodytes
XP_001151660
275
31822
Y41
R
K
N
S
P
L
H
Y
Y
Q
R
L
E
I
V
Rhesus Macaque
Macaca mulatta
XP_001111835
573
63247
Y339
R
K
N
S
P
L
H
Y
Y
R
R
L
E
I
I
Dog
Lupus familis
XP_536531
532
59743
H298
G
K
S
S
Q
L
T
H
Y
H
Q
R
L
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ2
278
32370
S41
G
L
K
N
N
R
L
S
R
Q
Q
E
R
I
E
Rat
Rattus norvegicus
Q497B2
278
32319
S41
G
L
K
K
N
R
L
S
L
Q
Q
Q
R
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506350
563
61793
G227
A
R
S
R
F
S
R
G
A
E
R
L
E
L
I
Chicken
Gallus gallus
XP_417866
281
32113
N41
A
S
K
K
S
Q
K
N
Y
C
F
Q
R
L
D
Frog
Xenopus laevis
Q6NS09
280
31983
N41
V
K
G
N
C
R
S
N
K
C
Y
D
R
L
E
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
R41
K
E
R
Q
V
G
D
R
E
R
Q
K
L
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
S41
N
G
R
Q
R
P
R
S
R
V
M
Y
C
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
45.7
42.8
N.A.
79.1
76.9
N.A.
32.1
58.3
62.8
53.7
N.A.
N.A.
N.A.
N.A.
33.8
Protein Similarity:
100
100
46.9
47.3
N.A.
88.4
85.9
N.A.
39.9
75
77.1
71.3
N.A.
N.A.
N.A.
N.A.
55.2
P-Site Identity:
100
100
86.6
26.6
N.A.
13.3
13.3
N.A.
20
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
53.3
N.A.
26.6
20
N.A.
53.3
13.3
20
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
19
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% D
% Glu:
0
10
0
0
0
0
0
0
10
10
0
10
37
10
28
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
28
10
10
0
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
28
10
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
28
% I
% Lys:
10
46
28
19
0
0
10
0
10
0
0
10
0
0
0
% K
% Leu:
0
19
0
0
0
37
19
0
10
0
0
37
19
37
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
28
19
19
0
0
19
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
28
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
19
10
10
0
0
0
37
37
19
0
0
0
% Q
% Arg:
28
10
19
10
10
28
19
10
19
19
37
10
37
0
0
% R
% Ser:
0
10
19
37
10
10
10
28
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
46
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _