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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C18orf25
All Species:
27.27
Human Site:
S219
Identified Species:
75
UniProt:
Q96B23
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B23
NP_001008240.1
403
43324
S219
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001084520
404
43460
S219
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Dog
Lupus familis
XP_852851
404
43408
S219
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH50
245
26427
P79
A
S
T
E
S
D
K
P
T
T
G
R
V
Y
E
Rat
Rattus norvegicus
NP_001100844
399
42663
S219
T
C
D
S
S
T
S
S
S
D
D
E
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507559
469
51241
S223
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Chicken
Gallus gallus
XP_414695
407
44001
S222
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Frog
Xenopus laevis
NP_001080355
402
43743
S222
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Zebra Danio
Brachydanio rerio
NP_991243
335
35800
R170
V
R
G
P
R
S
Q
R
Q
K
Q
R
M
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.7
98.2
N.A.
58.5
93
N.A.
70.1
85.7
71.9
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.5
99.2
N.A.
59.5
94.7
N.A.
75.4
90.9
81.3
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
100
100
100
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
13.3
100
N.A.
100
100
100
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
78
0
0
12
0
0
0
78
78
67
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
0
0
0
0
12
78
78
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
12
0
12
0
0
0
12
% Q
% Arg:
0
12
0
0
12
0
0
12
0
0
0
23
0
12
0
% R
% Ser:
0
12
0
78
89
12
78
78
78
0
0
0
0
0
0
% S
% Thr:
78
0
12
0
0
78
0
0
12
12
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
78
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _