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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC8
All Species:
37.27
Human Site:
S116
Identified Species:
82
UniProt:
Q96B26
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B26
NP_852480.1
276
30040
S116
I
A
D
V
I
E
N
S
Q
I
I
Q
K
E
D
Chimpanzee
Pan troglodytes
XP_522661
276
30031
S116
I
A
D
V
I
E
N
S
Q
I
I
Q
K
E
D
Rhesus Macaque
Macaca mulatta
XP_001085228
276
30003
S116
I
A
D
V
I
E
N
S
Q
I
I
Q
K
E
D
Dog
Lupus familis
XP_534492
276
29977
S116
I
A
D
V
I
E
N
S
Q
I
I
Q
K
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D753
276
29931
S116
I
A
D
V
V
D
N
S
Q
V
I
K
K
E
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511768
276
29817
S116
I
N
D
V
I
E
N
S
Q
L
I
A
K
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088781
276
29933
S116
M
A
D
V
I
D
N
S
Q
M
L
L
K
E
D
Zebra Danio
Brachydanio rerio
NP_001002865
277
30364
S116
I
A
D
V
I
E
S
S
D
L
I
N
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624000
281
30977
S116
V
E
N
I
L
R
N
S
A
A
I
D
L
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796992
275
29794
S116
V
A
D
T
L
L
S
S
N
L
L
N
Y
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05636
305
33943
S115
I
E
K
S
V
R
R
S
G
A
L
D
V
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.2
97.4
N.A.
92
N.A.
N.A.
88
N.A.
75.3
70.4
N.A.
N.A.
45.2
N.A.
59.7
Protein Similarity:
100
99.6
99.2
98.5
N.A.
97
N.A.
N.A.
93.1
N.A.
84.7
84.8
N.A.
N.A.
67.2
N.A.
80
P-Site Identity:
100
100
100
100
N.A.
73.3
N.A.
N.A.
80
N.A.
66.6
60
N.A.
N.A.
20
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
93.3
80
N.A.
N.A.
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
73
0
0
0
0
0
0
10
19
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
82
0
0
19
0
0
10
0
0
19
0
0
73
% D
% Glu:
0
19
0
0
0
55
0
0
0
0
0
0
0
91
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
73
0
0
10
64
0
0
0
0
37
73
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
10
64
10
0
% K
% Leu:
0
0
0
0
19
10
0
0
0
28
28
10
19
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
73
0
10
0
0
19
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
64
0
0
37
0
0
0
% Q
% Arg:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
19
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
0
73
19
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _