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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOSC8 All Species: 39.7
Human Site: S90 Identified Species: 87.33
UniProt: Q96B26 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96B26 NP_852480.1 276 30040 S90 V D L P P L C S S R F R S G P
Chimpanzee Pan troglodytes XP_522661 276 30031 S90 V D L P P L C S S R F R S G P
Rhesus Macaque Macaca mulatta XP_001085228 276 30003 S90 V D L P P L C S S R F R S G P
Dog Lupus familis XP_534492 276 29977 S90 V D L P P L C S S R F R S G P
Cat Felis silvestris
Mouse Mus musculus Q9D753 276 29931 S90 V D L P P L C S S R F R T G P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511768 276 29817 S90 V D L P P L C S S R F R P G P
Chicken Gallus gallus
Frog Xenopus laevis NP_001088781 276 29933 S90 V D L S P L C S S Q F R P G P
Zebra Danio Brachydanio rerio NP_001002865 277 30364 S90 V D L P P L C S S R F R A G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624000 281 30977 S90 I E L P P L C S P K F R P G P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796992 275 29794 S90 V D L P P L C S A Q F K P G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05636 305 33943 S89 E I S P M A G S Q F E N G N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.2 97.4 N.A. 92 N.A. N.A. 88 N.A. 75.3 70.4 N.A. N.A. 45.2 N.A. 59.7
Protein Similarity: 100 99.6 99.2 98.5 N.A. 97 N.A. N.A. 93.1 N.A. 84.7 84.8 N.A. N.A. 67.2 N.A. 80
P-Site Identity: 100 100 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. 80 93.3 N.A. N.A. 66.6 N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 86.6 100 N.A. N.A. 86.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 10 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 % C
% Asp: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 91 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 10 91 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % K
% Leu: 0 0 91 0 0 91 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 0 0 0 91 91 0 0 0 10 0 0 0 37 0 91 % P
% Gln: 0 0 0 0 0 0 0 0 10 19 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 64 0 82 0 0 0 % R
% Ser: 0 0 10 10 0 0 0 100 73 0 0 0 37 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _