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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOSC8 All Species: 38.18
Human Site: Y78 Identified Species: 84
UniProt: Q96B26 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96B26 NP_852480.1 276 30040 Y78 T D A P D K G Y V V P N V D L
Chimpanzee Pan troglodytes XP_522661 276 30031 Y78 T D A P D K G Y V V P N V D L
Rhesus Macaque Macaca mulatta XP_001085228 276 30003 Y78 T D A P D K G Y V V P N V D L
Dog Lupus familis XP_534492 276 29977 Y78 T D A P D K G Y V V P N V D L
Cat Felis silvestris
Mouse Mus musculus Q9D753 276 29931 Y78 V D A P D R G Y V V P N V D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511768 276 29817 Y78 G D A P N K G Y V V P N V D L
Chicken Gallus gallus
Frog Xenopus laevis NP_001088781 276 29933 Y78 A D A P N K G Y V V P N V D L
Zebra Danio Brachydanio rerio NP_001002865 277 30364 Y78 S E A Q N K G Y L V P N V D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624000 281 30977 Y78 A E S P E C G Y I V P N I E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796992 275 29794 Y78 V E E P K K G Y L V P N V D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05636 305 33943 F77 D R P F E G L F V I S T E I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.2 97.4 N.A. 92 N.A. N.A. 88 N.A. 75.3 70.4 N.A. N.A. 45.2 N.A. 59.7
Protein Similarity: 100 99.6 99.2 98.5 N.A. 97 N.A. N.A. 93.1 N.A. 84.7 84.8 N.A. N.A. 67.2 N.A. 80
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 86.6 N.A. 86.6 66.6 N.A. N.A. 46.6 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 73 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 64 0 0 46 0 0 0 0 0 0 0 0 82 0 % D
% Glu: 0 28 10 0 19 0 0 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 10 91 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 0 10 10 0 % I
% Lys: 0 0 0 0 10 73 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 19 0 0 0 0 0 91 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 28 0 0 0 0 0 0 91 0 0 0 % N
% Pro: 0 0 10 82 0 0 0 0 0 0 91 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 0 0 0 0 0 10 0 0 0 10 % S
% Thr: 37 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 19 0 0 0 0 0 0 0 73 91 0 0 82 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _