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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN23
All Species:
8.79
Human Site:
S206
Identified Species:
21.48
UniProt:
Q96B33
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B33
NP_919260.2
292
31915
S206
G
P
R
R
S
S
V
S
T
I
Q
V
E
W
P
Chimpanzee
Pan troglodytes
XP_528065
290
31820
S206
G
P
R
R
S
S
V
S
T
I
Q
V
E
W
P
Rhesus Macaque
Macaca mulatta
XP_001091185
289
31502
I204
R
R
S
S
V
S
T
I
Q
V
E
W
P
E
P
Dog
Lupus familis
XP_851151
187
19670
P120
V
R
C
W
R
E
E
P
R
S
A
L
A
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7D7
296
32443
S206
G
P
R
R
S
S
I
S
T
V
Y
V
D
W
P
Rat
Rattus norvegicus
Q63400
219
23296
P152
D
F
Y
N
P
L
V
P
E
A
Q
K
R
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511039
132
14342
V65
S
W
E
R
Q
C
L
V
P
D
K
W
A
Y
S
Chicken
Gallus gallus
XP_426312
233
25118
L166
L
S
Y
L
G
S
C
L
E
I
L
G
G
V
A
Frog
Xenopus laevis
NP_001087400
213
22866
F146
A
N
T
I
I
R
D
F
Y
N
P
L
V
V
D
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
N141
I
P
V
C
W
S
A
N
S
V
I
K
D
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
90
46.9
N.A.
78.3
21.2
N.A.
26.7
47.5
20.8
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
92.8
50.6
N.A.
84.1
33.9
N.A.
33.2
57.8
38
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
73.3
13.3
N.A.
6.6
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
93.3
13.3
N.A.
26.6
13.3
6.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
10
10
0
20
0
10
% A
% Cys:
0
0
10
10
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
10
0
0
20
0
10
% D
% Glu:
0
0
10
0
0
10
10
0
20
0
10
0
20
20
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
30
0
0
0
10
0
0
0
0
0
0
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
10
0
10
10
0
30
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
20
0
0
0
% K
% Leu:
10
0
0
10
0
10
10
10
0
0
10
20
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
10
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
0
40
0
0
10
0
0
20
10
0
10
0
10
0
40
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
30
0
0
0
0
% Q
% Arg:
10
20
30
40
10
10
0
0
10
0
0
0
10
0
0
% R
% Ser:
10
10
10
10
30
60
0
30
10
10
0
0
0
0
10
% S
% Thr:
0
0
10
0
0
0
10
0
30
0
0
0
0
0
0
% T
% Val:
10
0
10
0
10
0
30
10
0
30
0
30
10
20
0
% V
% Trp:
0
10
0
10
10
0
0
0
0
0
0
20
0
30
0
% W
% Tyr:
0
0
20
0
0
0
0
0
10
0
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _