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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKT1S1
All Species:
21.82
Human Site:
S116
Identified Species:
60
UniProt:
Q96B36
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B36
NP_001092102.1
256
27383
S116
E
P
T
E
T
E
T
S
G
E
Q
L
G
I
S
Chimpanzee
Pan troglodytes
XP_001173520
276
29272
S136
E
P
T
E
T
E
T
S
G
E
Q
L
G
I
S
Rhesus Macaque
Macaca mulatta
XP_001115706
256
27335
S116
E
P
T
E
T
E
T
S
G
E
Q
L
G
V
S
Dog
Lupus familis
XP_851369
256
27475
S116
E
R
T
E
T
E
T
S
G
E
R
L
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1F4
257
27465
S117
E
P
T
E
T
E
T
S
G
E
R
L
G
G
S
Rat
Rattus norvegicus
NP_001099729
257
27568
S117
E
P
T
E
T
E
T
S
G
E
R
L
G
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519984
80
8428
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088244
278
31592
D138
L
E
A
P
D
E
E
D
Y
D
Y
N
K
Q
L
Zebra Danio
Brachydanio rerio
XP_692511
354
38348
G215
D
E
E
E
D
L
D
G
R
R
R
N
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
98.8
93.7
N.A.
93.3
92.6
N.A.
26.5
N.A.
38.4
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.3
99.6
95.6
N.A.
94.9
94.5
N.A.
28.5
N.A.
51.4
43.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
23
0
12
12
0
12
0
0
0
0
0
% D
% Glu:
67
23
12
78
0
78
12
0
0
67
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
67
0
0
0
67
23
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
0
0
0
0
12
0
0
0
0
0
67
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
23
0
12
0
% N
% Pro:
0
56
0
12
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
34
0
0
12
0
% Q
% Arg:
0
12
0
0
0
0
0
0
12
12
45
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
67
% S
% Thr:
0
0
67
0
67
0
67
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _