Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM18 All Species: 10.3
Human Site: S48 Identified Species: 18.89
UniProt: Q96B42 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96B42 NP_690047.2 140 16265 S48 L T C L S S R S Y R L Q I G H
Chimpanzee Pan troglodytes XP_001168386 424 46160 S332 L T C L S S R S Y R L Q I G H
Rhesus Macaque Macaca mulatta XP_001095085 66 8138
Dog Lupus familis XP_848731 411 46016 R321 L T C L S S Q R Y K L Q V G H
Cat Felis silvestris
Mouse Mus musculus Q3TUD9 140 16507 R48 L T C F S S Q R Y K L Q I G H
Rat Rattus norvegicus Q6DGF8 140 16529 R48 L T C F S A Q R Y K L Q I G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F410 142 16450 H52 L T C F S F Q H Y R V Q I G H
Frog Xenopus laevis Q4V7N7 136 15939 S59 L L M V V L V S C A E Y I N E
Zebra Danio Brachydanio rerio Q641M3 152 17799 Y59 F T L L S C K Y Y R I Q I C H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725169 151 17335 S48 T A L L S R N S S N F Q V F L
Honey Bee Apis mellifera XP_624837 155 17727 H49 T A L M T R N H A N F Q I M L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002327230 158 18217 H71 L T V V S R K H I N F Q M S F
Maize Zea mays NP_001150219 179 20090 N87 V T I I S R R N I N F Q L I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33 45.7 28.9 N.A. 77.8 77.8 N.A. N.A. 66.1 57.8 50.6 N.A. 40.4 41.2 N.A. N.A.
Protein Similarity: 100 33 46.4 31.8 N.A. 88.5 89.2 N.A. N.A. 78.8 74.2 66.4 N.A. 53.6 58.7 N.A. N.A.
P-Site Identity: 100 100 0 73.3 N.A. 73.3 66.6 N.A. N.A. 66.6 20 53.3 N.A. 26.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 0 93.3 N.A. 86.6 86.6 N.A. N.A. 80 26.6 66.6 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: 34.1 31.8 N.A. N.A. N.A. N.A.
Protein Similarity: 51.9 49.7 N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 26.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 46.6 53.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 8 0 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 47 0 0 8 0 0 8 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 8 0 0 24 0 8 0 0 0 0 31 0 0 8 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % G
% His: 0 0 0 0 0 0 0 24 0 0 0 0 0 0 54 % H
% Ile: 0 0 8 8 0 0 0 0 16 0 8 0 62 8 0 % I
% Lys: 0 0 0 0 0 0 16 0 0 24 0 0 0 0 0 % K
% Leu: 62 8 24 39 0 8 0 0 0 0 39 0 8 0 24 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 0 0 0 0 0 0 16 8 0 31 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 31 0 0 0 0 85 0 0 0 % Q
% Arg: 0 0 0 0 0 31 24 24 0 31 0 0 0 0 0 % R
% Ser: 0 0 0 0 77 31 0 31 8 0 0 0 0 8 0 % S
% Thr: 16 70 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 8 16 8 0 8 0 0 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 54 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _