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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM18
All Species:
25.45
Human Site:
Y49
Identified Species:
46.67
UniProt:
Q96B42
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B42
NP_690047.2
140
16265
Y49
T
C
L
S
S
R
S
Y
R
L
Q
I
G
H
F
Chimpanzee
Pan troglodytes
XP_001168386
424
46160
Y333
T
C
L
S
S
R
S
Y
R
L
Q
I
G
H
F
Rhesus Macaque
Macaca mulatta
XP_001095085
66
8138
Dog
Lupus familis
XP_848731
411
46016
Y322
T
C
L
S
S
Q
R
Y
K
L
Q
V
G
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3TUD9
140
16507
Y49
T
C
F
S
S
Q
R
Y
K
L
Q
I
G
H
F
Rat
Rattus norvegicus
Q6DGF8
140
16529
Y49
T
C
F
S
A
Q
R
Y
K
L
Q
I
G
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F410
142
16450
Y53
T
C
F
S
F
Q
H
Y
R
V
Q
I
G
H
F
Frog
Xenopus laevis
Q4V7N7
136
15939
C60
L
M
V
V
L
V
S
C
A
E
Y
I
N
E
F
Zebra Danio
Brachydanio rerio
Q641M3
152
17799
Y60
T
L
L
S
C
K
Y
Y
R
I
Q
I
C
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725169
151
17335
S49
A
L
L
S
R
N
S
S
N
F
Q
V
F
L
F
Honey Bee
Apis mellifera
XP_624837
155
17727
A50
A
L
M
T
R
N
H
A
N
F
Q
I
M
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327230
158
18217
I72
T
V
V
S
R
K
H
I
N
F
Q
M
S
F
F
Maize
Zea mays
NP_001150219
179
20090
I88
T
I
I
S
R
R
N
I
N
F
Q
L
I
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
45.7
28.9
N.A.
77.8
77.8
N.A.
N.A.
66.1
57.8
50.6
N.A.
40.4
41.2
N.A.
N.A.
Protein Similarity:
100
33
46.4
31.8
N.A.
88.5
89.2
N.A.
N.A.
78.8
74.2
66.4
N.A.
53.6
58.7
N.A.
N.A.
P-Site Identity:
100
100
0
73.3
N.A.
73.3
66.6
N.A.
N.A.
66.6
20
60
N.A.
33.3
20
N.A.
N.A.
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
26.6
73.3
N.A.
40
33.3
N.A.
N.A.
Percent
Protein Identity:
34.1
31.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.9
49.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
46.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
47
0
0
8
0
0
8
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
24
0
8
0
0
0
0
31
0
0
8
8
85
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% G
% His:
0
0
0
0
0
0
24
0
0
0
0
0
0
54
0
% H
% Ile:
0
8
8
0
0
0
0
16
0
8
0
62
8
0
0
% I
% Lys:
0
0
0
0
0
16
0
0
24
0
0
0
0
0
0
% K
% Leu:
8
24
39
0
8
0
0
0
0
39
0
8
0
24
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
16
8
0
31
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
31
0
0
0
0
85
0
0
0
0
% Q
% Arg:
0
0
0
0
31
24
24
0
31
0
0
0
0
0
0
% R
% Ser:
0
0
0
77
31
0
31
8
0
0
0
0
8
0
8
% S
% Thr:
70
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
16
8
0
8
0
0
0
8
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _