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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM18
All Species:
23.03
Human Site:
Y83
Identified Species:
42.22
UniProt:
Q96B42
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B42
NP_690047.2
140
16265
Y83
N
W
R
L
F
S
K
Y
Q
Y
F
D
S
R
G
Chimpanzee
Pan troglodytes
XP_001168386
424
46160
Y367
N
W
R
L
F
S
K
Y
Q
Y
F
D
S
R
G
Rhesus Macaque
Macaca mulatta
XP_001095085
66
8138
S24
M
F
I
S
I
V
F
S
A
P
L
L
V
N
A
Dog
Lupus familis
XP_848731
411
46016
Y356
N
W
R
L
F
S
K
Y
Q
Y
F
D
S
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TUD9
140
16507
Y83
N
W
R
L
F
S
K
Y
Q
Y
F
D
S
R
G
Rat
Rattus norvegicus
Q6DGF8
140
16529
Y83
N
W
R
L
F
A
K
Y
Q
Y
F
D
S
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F410
142
16450
Y87
N
W
R
L
F
S
K
Y
Q
Y
F
D
S
R
G
Frog
Xenopus laevis
Q4V7N7
136
15939
A94
F
I
S
L
A
F
S
A
P
L
L
C
N
T
I
Zebra Danio
Brachydanio rerio
Q641M3
152
17799
F94
N
W
R
S
F
S
K
F
Q
Y
F
D
S
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725169
151
17335
Q83
N
W
S
S
F
S
R
Q
Q
Y
F
D
S
N
G
Honey Bee
Apis mellifera
XP_624837
155
17727
Q84
N
W
M
L
F
S
R
Q
Q
Y
F
D
S
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002327230
158
18217
Q106
N
W
R
S
F
A
S
Q
N
Y
F
D
P
H
G
Maize
Zea mays
NP_001150219
179
20090
Q122
N
W
K
S
F
S
T
Q
N
Y
F
D
P
Q
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
45.7
28.9
N.A.
77.8
77.8
N.A.
N.A.
66.1
57.8
50.6
N.A.
40.4
41.2
N.A.
N.A.
Protein Similarity:
100
33
46.4
31.8
N.A.
88.5
89.2
N.A.
N.A.
78.8
74.2
66.4
N.A.
53.6
58.7
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
93.3
N.A.
N.A.
100
6.6
80
N.A.
66.6
73.3
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
100
13.3
93.3
N.A.
73.3
80
N.A.
N.A.
Percent
Protein Identity:
34.1
31.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.9
49.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
53.3
53.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
66.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
16
0
8
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
85
8
8
8
0
0
85
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
0
54
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
62
0
0
0
0
0
8
16
8
0
0
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
85
0
0
0
0
0
0
0
16
0
0
0
8
24
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
8
0
0
16
0
0
% P
% Gln:
0
0
0
0
0
0
0
31
70
0
0
0
0
8
0
% Q
% Arg:
0
0
62
0
0
0
16
0
0
0
0
0
0
47
0
% R
% Ser:
0
0
16
39
0
70
16
8
0
0
0
0
70
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
85
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
85
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _