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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM18 All Species: 39.7
Human Site: Y85 Identified Species: 72.78
UniProt: Q96B42 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96B42 NP_690047.2 140 16265 Y85 R L F S K Y Q Y F D S R G M F
Chimpanzee Pan troglodytes XP_001168386 424 46160 Y369 R L F S K Y Q Y F D S R G M F
Rhesus Macaque Macaca mulatta XP_001095085 66 8138 P26 I S I V F S A P L L V N A M I
Dog Lupus familis XP_848731 411 46016 Y358 R L F S K Y Q Y F D S R G M F
Cat Felis silvestris
Mouse Mus musculus Q3TUD9 140 16507 Y85 R L F S K Y Q Y F D S R G M F
Rat Rattus norvegicus Q6DGF8 140 16529 Y85 R L F A K Y Q Y F D S R G M F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F410 142 16450 Y89 R L F S K Y Q Y F D S R G M F
Frog Xenopus laevis Q4V7N7 136 15939 L96 S L A F S A P L L C N T I I I
Zebra Danio Brachydanio rerio Q641M3 152 17799 Y96 R S F S K F Q Y F D S K G M F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725169 151 17335 Y85 S S F S R Q Q Y F D S N G L F
Honey Bee Apis mellifera XP_624837 155 17727 Y86 M L F S R Q Q Y F D S N G L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002327230 158 18217 Y108 R S F A S Q N Y F D P H G L F
Maize Zea mays NP_001150219 179 20090 Y124 K S F S T Q N Y F D P Q G L F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33 45.7 28.9 N.A. 77.8 77.8 N.A. N.A. 66.1 57.8 50.6 N.A. 40.4 41.2 N.A. N.A.
Protein Similarity: 100 33 46.4 31.8 N.A. 88.5 89.2 N.A. N.A. 78.8 74.2 66.4 N.A. 53.6 58.7 N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 93.3 N.A. N.A. 100 6.6 80 N.A. 60 66.6 N.A. N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. 100 20 93.3 N.A. 73.3 80 N.A. N.A.
Percent
Protein Identity: 34.1 31.8 N.A. N.A. N.A. N.A.
Protein Similarity: 51.9 49.7 N.A. N.A. N.A. N.A.
P-Site Identity: 46.6 46.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 60 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 16 0 8 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 85 8 8 8 0 0 85 0 0 0 0 0 85 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 85 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 0 0 0 8 8 16 % I
% Lys: 8 0 0 0 54 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 62 0 0 0 0 0 8 16 8 0 0 0 31 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 62 0 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 8 24 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 8 0 0 16 0 0 0 0 % P
% Gln: 0 0 0 0 0 31 70 0 0 0 0 8 0 0 0 % Q
% Arg: 62 0 0 0 16 0 0 0 0 0 0 47 0 0 0 % R
% Ser: 16 39 0 70 16 8 0 0 0 0 70 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 47 0 85 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _