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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM186
All Species:
15.15
Human Site:
S44
Identified Species:
37.04
UniProt:
Q96B77
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B77
NP_056236.2
213
24893
S44
V
G
S
S
S
P
I
S
K
E
K
L
P
N
A
Chimpanzee
Pan troglodytes
XP_510804
213
24845
S44
V
G
S
S
S
P
I
S
K
E
K
L
P
N
A
Rhesus Macaque
Macaca mulatta
XP_001103641
213
24963
S44
V
G
S
R
S
P
T
S
K
E
K
P
P
N
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR76
216
24613
S44
V
G
S
R
S
P
H
S
R
E
K
S
P
G
T
Rat
Rattus norvegicus
Q4KLZ1
216
24622
S44
V
G
S
R
S
P
P
S
Q
E
K
P
P
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506629
223
24832
S53
P
G
A
Q
K
E
L
S
T
T
T
R
G
P
P
Chicken
Gallus gallus
XP_414939
252
28417
G86
R
W
A
P
A
A
A
G
P
Q
K
A
A
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DI94
228
25702
P62
T
H
T
T
R
I
H
P
A
S
F
S
S
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610846
204
22779
K38
F
A
T
E
A
A
G
K
R
T
E
T
E
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796429
253
29017
R87
T
V
R
G
N
E
S
R
D
K
V
A
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.1
N.A.
N.A.
70.3
70.3
N.A.
50.2
36.1
N.A.
34.6
N.A.
26.7
N.A.
N.A.
33.9
Protein Similarity:
100
99.5
92
N.A.
N.A.
81.9
82.8
N.A.
65
53.5
N.A.
54.8
N.A.
45
N.A.
N.A.
53.3
P-Site Identity:
100
100
73.3
N.A.
N.A.
60
60
N.A.
13.3
6.6
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
73.3
N.A.
N.A.
66.6
66.6
N.A.
26.6
33.3
N.A.
20
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
20
0
20
20
10
0
10
0
0
20
10
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
10
20
0
% D
% Glu:
0
0
0
10
0
20
0
0
0
50
10
0
10
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
60
0
10
0
0
10
10
0
0
0
0
10
30
10
% G
% His:
0
10
0
0
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
10
30
10
60
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
20
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
30
0
% N
% Pro:
10
0
0
10
0
50
10
10
10
0
0
20
50
10
10
% P
% Gln:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
20
% Q
% Arg:
10
0
10
30
10
0
0
10
20
0
0
10
0
0
0
% R
% Ser:
0
0
50
20
50
0
10
60
0
10
0
20
10
0
10
% S
% Thr:
20
0
20
10
0
0
10
0
10
20
10
10
0
0
20
% T
% Val:
50
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _