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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM186
All Species:
12.42
Human Site:
T203
Identified Species:
30.37
UniProt:
Q96B77
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B77
NP_056236.2
213
24893
T203
I
L
D
R
E
R
F
T
Q
V
F
G
V
H
Q
Chimpanzee
Pan troglodytes
XP_510804
213
24845
T203
I
L
D
R
E
R
F
T
Q
V
F
G
V
H
Q
Rhesus Macaque
Macaca mulatta
XP_001103641
213
24963
T203
I
L
D
R
E
R
F
T
Q
V
F
G
R
H
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR76
216
24613
A203
I
L
D
R
E
R
F
A
Q
V
F
G
T
L
A
Rat
Rattus norvegicus
Q4KLZ1
216
24622
S203
I
L
D
R
D
R
F
S
Q
V
F
G
T
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506629
223
24832
G212
V
L
D
H
R
R
F
G
Q
V
F
G
P
S
D
Chicken
Gallus gallus
XP_414939
252
28417
M245
I
V
D
R
Q
K
F
M
Q
I
F
G
E
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B3DI94
228
25702
G221
V
V
D
R
H
A
F
G
K
V
F
G
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610846
204
22779
L197
G
H
V
S
D
R
Q
L
F
E
G
L
F
G
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796429
253
29017
E246
V
I
D
V
E
V
F
E
N
V
F
G
R
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
90.1
N.A.
N.A.
70.3
70.3
N.A.
50.2
36.1
N.A.
34.6
N.A.
26.7
N.A.
N.A.
33.9
Protein Similarity:
100
99.5
92
N.A.
N.A.
81.9
82.8
N.A.
65
53.5
N.A.
54.8
N.A.
45
N.A.
N.A.
53.3
P-Site Identity:
100
100
93.3
N.A.
N.A.
73.3
66.6
N.A.
53.3
53.3
N.A.
40
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
73.3
80
N.A.
60
80
N.A.
60
N.A.
13.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
90
0
20
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
50
0
0
10
0
10
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
90
0
10
0
90
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
0
20
0
0
10
90
0
10
0
% G
% His:
0
10
0
10
10
0
0
0
0
0
0
0
0
30
0
% H
% Ile:
60
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
60
0
0
0
0
0
10
0
0
0
10
0
40
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
10
0
10
0
70
0
0
0
0
0
50
% Q
% Arg:
0
0
0
70
10
70
0
0
0
0
0
0
20
0
0
% R
% Ser:
0
0
0
10
0
0
0
10
0
0
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
30
0
0
0
0
20
0
0
% T
% Val:
30
20
10
10
0
10
0
0
0
80
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _