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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3KBP1
All Species:
18.48
Human Site:
S174
Identified Species:
45.19
UniProt:
Q96B97
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B97
NP_001019837.1
665
73126
S174
D
E
Q
L
S
K
S
S
L
R
E
T
T
G
S
Chimpanzee
Pan troglodytes
XP_520965
672
73799
S174
D
E
Q
L
S
K
S
S
L
R
E
T
T
G
S
Rhesus Macaque
Macaca mulatta
XP_001085866
626
68239
S137
D
E
Q
L
S
K
S
S
L
R
E
T
T
G
S
Dog
Lupus familis
XP_849391
628
68475
S137
D
E
Q
L
S
K
S
S
L
R
E
T
T
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R550
709
78152
R174
D
E
Q
L
S
K
S
R
P
E
G
F
L
P
A
Rat
Rattus norvegicus
Q925Q9
709
78067
R174
D
E
Q
L
S
K
S
R
P
E
G
F
L
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
S202
E
E
Q
L
I
K
P
S
L
R
E
T
T
G
S
Chicken
Gallus gallus
Q5ZLR6
764
85889
Q228
L
K
G
L
E
S
T
Q
L
T
K
N
Y
Y
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666707
602
66567
G145
Q
E
E
R
G
K
R
G
I
K
D
S
T
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195816
853
91426
T199
A
V
S
S
S
G
G
T
T
P
M
E
E
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.3
89.3
N.A.
88.2
87.7
N.A.
80.5
20
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
30
Protein Similarity:
100
92.8
90.9
91.2
N.A.
91.1
90.4
N.A.
87.5
36.2
N.A.
65.1
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
100
100
N.A.
46.6
46.6
N.A.
80
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
53.3
53.3
N.A.
86.6
33.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
80
10
0
10
0
0
0
0
20
50
10
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
10
0
10
10
10
10
0
0
20
0
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
80
0
0
0
10
10
0
0
0
0
% K
% Leu:
10
0
0
80
0
0
0
0
60
0
0
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
20
10
0
0
0
20
10
% P
% Gln:
10
0
70
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
10
20
0
50
0
0
0
0
0
% R
% Ser:
0
0
10
10
70
10
60
50
0
0
0
10
0
0
60
% S
% Thr:
0
0
0
0
0
0
10
10
10
10
0
50
60
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _