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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3KBP1
All Species:
11.52
Human Site:
T593
Identified Species:
28.15
UniProt:
Q96B97
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96B97
NP_001019837.1
665
73126
T593
N
S
P
S
L
F
G
T
E
G
K
P
K
M
E
Chimpanzee
Pan troglodytes
XP_520965
672
73799
T600
N
S
P
S
L
F
G
T
E
G
K
P
K
M
E
Rhesus Macaque
Macaca mulatta
XP_001085866
626
68239
X556
N
S
P
S
L
F
G
X
X
X
X
X
X
X
A
Dog
Lupus familis
XP_849391
628
68475
G555
A
N
S
P
S
L
F
G
S
E
G
K
P
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8R550
709
78152
T637
S
S
P
S
L
F
S
T
E
G
K
P
K
M
E
Rat
Rattus norvegicus
Q925Q9
709
78067
A637
S
S
P
S
L
F
S
A
E
G
K
A
K
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514038
690
76640
G620
P
L
L
F
S
A
E
G
K
P
K
T
E
H
L
Chicken
Gallus gallus
Q5ZLR6
764
85889
A645
T
A
A
L
E
E
D
A
Q
I
L
K
V
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666707
602
66567
S531
G
A
G
L
R
P
H
S
P
S
V
D
A
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195816
853
91426
T776
P
R
P
A
V
G
V
T
K
T
T
P
S
I
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
90.3
89.3
N.A.
88.2
87.7
N.A.
80.5
20
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
30
Protein Similarity:
100
92.8
90.9
91.2
N.A.
91.1
90.4
N.A.
87.5
36.2
N.A.
65.1
N.A.
N.A.
N.A.
N.A.
45.7
P-Site Identity:
100
100
46.6
0
N.A.
86.6
66.6
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
46.6
6.6
N.A.
93.3
73.3
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
10
10
0
10
0
20
0
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
10
10
10
0
40
10
0
0
10
0
50
% E
% Phe:
0
0
0
10
0
50
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
10
30
20
0
40
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
20
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
50
20
40
10
0
% K
% Leu:
0
10
10
20
50
10
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
10
% M
% Asn:
30
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
20
0
60
10
0
10
0
0
10
10
0
40
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
20
50
10
50
20
0
20
10
10
10
0
0
10
0
0
% S
% Thr:
10
0
0
0
0
0
0
40
0
10
10
10
0
10
0
% T
% Val:
0
0
0
0
10
0
10
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _