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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLCO4A1 All Species: 21.52
Human Site: S258 Identified Species: 47.33
UniProt: Q96BD0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BD0 NP_057438.3 722 77193 S258 Y L D E N V K S S C S P V Y I
Chimpanzee Pan troglodytes XP_001145778 722 76927 S258 Y L D E N V K S S C S P V Y I
Rhesus Macaque Macaca mulatta XP_001087895 713 76269 S249 Y L D E N V K S S Y S P V Y I
Dog Lupus familis XP_543087 808 84989 S337 Y L D E N V K S S Y S P V Y I
Cat Felis silvestris
Mouse Mus musculus Q8K078 723 77650 S260 Y L D E N V K S S Y S P I Y I
Rat Rattus norvegicus Q99N01 723 77615 N260 G V T Y L D E N V K S S Y S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506429 681 73992 A244 A A I L G P A A G Y L I G G S
Chicken Gallus gallus NP_001026027 587 62766 G154 T F V S Y F G G N G H K P R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696263 725 78339 S253 Y L D E N V K S N Y A P V Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609055 692 74940 G245 K M S S V Y L G I Y Y T M A T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198059 772 84602 G297 A I L G P A L G Y L L G G V F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 94.3 69.9 N.A. 74.4 73.3 N.A. 65.3 54.8 N.A. 60.6 N.A. 41 N.A. N.A. 36.9
Protein Similarity: 100 96.5 95.1 76.2 N.A. 82 81 N.A. 75.2 64.4 N.A. 72.1 N.A. 58.3 N.A. N.A. 53.1
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 6.6 N.A. 0 0 N.A. 80 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 26.6 N.A. 6.6 6.6 N.A. 93.3 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 0 10 10 10 0 0 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 0 0 55 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 55 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 10 10 0 10 28 10 10 0 10 19 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 10 10 0 0 0 0 0 10 0 0 10 10 0 55 % I
% Lys: 10 0 0 0 0 0 55 0 0 10 0 10 0 0 0 % K
% Leu: 0 55 10 10 10 0 19 0 0 10 19 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 55 0 0 10 19 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 10 0 0 0 0 0 55 10 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 10 19 0 0 0 55 46 0 55 10 0 10 10 % S
% Thr: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 10 % T
% Val: 0 10 10 0 10 55 0 0 10 0 0 0 46 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 55 0 0 10 10 10 0 0 10 55 10 0 10 55 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _