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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLCO4A1 All Species: 5.45
Human Site: S355 Identified Species: 12
UniProt: Q96BD0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BD0 NP_057438.3 722 77193 S355 E M H Q L K D S S R G E A S N
Chimpanzee Pan troglodytes XP_001145778 722 76927 L355 D M D I L G D L C T P E R A E
Rhesus Macaque Macaca mulatta XP_001087895 713 76269 G346 E M H Q L K D G S H G K A S N
Dog Lupus familis XP_543087 808 84989 S434 E T H Q L K D S G P T A V S N
Cat Felis silvestris
Mouse Mus musculus Q8K078 723 77650 H357 E T Q Q L K D H S R G A V S N
Rat Rattus norvegicus Q99N01 723 77615 L357 R A A E T Q Q L K D H S R D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506429 681 73992 S341 T V K D L P L S I W L L L K N
Chicken Gallus gallus NP_001026027 587 62766 P251 N V K T N Y S P V Y I A V F Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696263 725 78339 G350 E A H Q L K D G S Q V T A S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609055 692 74940 S342 T I S E A D D S S N V V R G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198059 772 84602 N394 Q R R N E A H N G H Q F E V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.5 94.3 69.9 N.A. 74.4 73.3 N.A. 65.3 54.8 N.A. 60.6 N.A. 41 N.A. N.A. 36.9
Protein Similarity: 100 96.5 95.1 76.2 N.A. 82 81 N.A. 75.2 64.4 N.A. 72.1 N.A. 58.3 N.A. N.A. 53.1
P-Site Identity: 100 26.6 80 60 N.A. 66.6 6.6 N.A. 20 0 N.A. 60 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 40 86.6 60 N.A. 66.6 20 N.A. 26.6 6.6 N.A. 73.3 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 0 10 10 0 0 0 0 0 28 28 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 10 10 0 10 64 0 0 10 0 0 0 10 10 % D
% Glu: 46 0 0 19 10 0 0 0 0 0 0 19 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % F
% Gly: 0 0 0 0 0 10 0 19 19 0 28 0 0 10 0 % G
% His: 0 0 37 0 0 0 10 10 0 19 10 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 0 10 0 10 0 0 0 0 % I
% Lys: 0 0 19 0 0 46 0 0 10 0 0 10 0 10 0 % K
% Leu: 0 0 0 0 64 0 10 19 0 0 10 10 10 0 10 % L
% Met: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 10 0 0 10 0 10 0 0 0 0 55 % N
% Pro: 0 0 0 0 0 10 0 10 0 10 10 0 0 0 0 % P
% Gln: 10 0 10 46 0 10 10 0 0 10 10 0 0 0 0 % Q
% Arg: 10 10 10 0 0 0 0 0 0 19 0 0 28 0 10 % R
% Ser: 0 0 10 0 0 0 10 37 46 0 0 10 0 46 0 % S
% Thr: 19 19 0 10 10 0 0 0 0 10 10 10 0 0 0 % T
% Val: 0 19 0 0 0 0 0 0 10 0 19 10 28 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _