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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF21A
All Species:
27.27
Human Site:
T225
Identified Species:
75
UniProt:
Q96BD5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BD5
NP_001095272.1
680
74854
T225
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Chimpanzee
Pan troglodytes
XP_001161616
681
74964
T226
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Rhesus Macaque
Macaca mulatta
XP_001112684
681
75007
T226
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Dog
Lupus familis
XP_540757
680
74858
T225
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPK0
659
72503
T234
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Rat
Rattus norvegicus
XP_342468
694
76496
T240
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507820
638
70589
R227
P
Q
F
I
P
P
P
R
L
T
P
R
P
N
F
Chicken
Gallus gallus
XP_421123
679
74910
T224
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693915
797
86009
P211
V
P
I
A
P
A
P
P
P
P
M
V
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
98.9
N.A.
91.3
94.3
N.A.
87.7
90.5
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.7
99.2
N.A.
93.6
95.9
N.A.
90.2
93.5
N.A.
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
0
0
0
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
78
0
12
0
0
0
0
0
0
0
0
0
78
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
78
12
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
78
0
12
0
0
0
0
78
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
78
0
12
0
% N
% Pro:
12
12
78
78
100
12
23
12
89
12
89
0
12
0
89
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
78
0
12
0
78
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
78
0
12
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _