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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPSB1
All Species:
40
Human Site:
Y226
Identified Species:
73.33
UniProt:
Q96BD6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BD6
NP_079382.2
273
30942
Y226
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Chimpanzee
Pan troglodytes
XP_525174
478
52950
Y431
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001113018
273
30174
Y226
H
C
E
V
T
M
R
Y
I
N
G
L
D
P
E
Dog
Lupus familis
XP_536736
435
48721
Y388
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5L7
273
30767
Y226
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Rat
Rattus norvegicus
Q5M877
264
28778
R220
R
I
R
Y
L
G
E
R
R
A
E
E
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505653
346
38337
Y226
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Chicken
Gallus gallus
XP_417599
273
31045
Y226
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Frog
Xenopus laevis
NP_001080202
273
30865
Y226
H
C
E
I
R
M
R
Y
L
N
G
L
D
P
E
Zebra Danio
Brachydanio rerio
NP_001020631
273
30786
Y226
H
C
E
I
R
I
R
Y
I
N
G
L
D
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6L9
255
28813
F212
C
E
D
N
T
L
S
F
E
K
N
Y
E
F
L
Honey Bee
Apis mellifera
XP_392605
431
46424
Y380
H
C
E
I
T
M
K
Y
I
G
G
L
D
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780123
272
30725
V226
C
E
I
T
L
K
Y
V
G
G
L
E
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
75
62
N.A.
98.5
50.9
N.A.
71
95.5
88.6
87.1
N.A.
36.2
43.8
N.A.
60
Protein Similarity:
100
57.1
84.6
62.7
N.A.
98.9
62.6
N.A.
74.5
97.4
94.1
94.1
N.A.
51.2
54
N.A.
76.9
P-Site Identity:
100
100
80
100
N.A.
100
0
N.A.
100
100
100
86.6
N.A.
0
73.3
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
0
N.A.
100
100
100
100
N.A.
26.6
86.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
16
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
77
0
0
% D
% Glu:
0
16
77
0
0
0
8
0
8
0
8
16
8
0
77
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
8
16
77
0
0
0
0
% G
% His:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
70
0
8
0
0
24
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
16
8
0
0
54
0
8
77
0
0
8
% L
% Met:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
70
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
16
77
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
8
0
62
0
70
8
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
8
24
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
77
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _