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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
15.45
Human Site:
S276
Identified Species:
28.33
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
S276
P
A
P
A
E
P
E
S
A
V
D
V
S
K
G
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
S276
P
A
P
A
E
P
G
S
A
V
D
V
S
K
G
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
A247
Q
P
P
S
T
L
A
A
E
L
P
T
S
S
A
Dog
Lupus familis
XP_536071
459
51107
S276
P
A
P
V
E
P
E
S
A
V
D
A
S
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
S273
P
A
A
L
E
P
E
S
A
V
D
V
S
R
E
Rat
Rattus norvegicus
NP_001012004
454
50810
S271
P
A
A
L
E
P
E
S
V
V
D
V
S
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
R243
R
G
E
R
S
G
P
R
G
Q
G
R
Q
S
C
Frog
Xenopus laevis
NP_001092170
377
42394
K210
P
D
R
A
T
L
K
K
Q
K
E
L
R
Q
I
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
P331
G
P
A
R
H
M
V
P
A
P
G
G
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
N207
M
P
P
S
E
L
L
N
A
P
E
F
K
V
T
Honey Bee
Apis mellifera
XP_624230
342
39095
P175
R
E
E
Q
E
K
L
P
Q
W
Q
Q
D
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
C199
A
D
K
S
L
G
N
C
P
V
C
R
K
I
F
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
E98
E
E
D
E
D
E
V
E
Y
D
D
H
G
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
80
N.A.
73.3
73.3
N.A.
N.A.
0
13.3
6.6
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
33.3
86.6
N.A.
80
80
N.A.
N.A.
0
40
13.3
N.A.
40
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
24
24
0
0
8
8
47
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% C
% Asp:
0
16
8
0
8
0
0
0
0
8
47
0
8
0
0
% D
% Glu:
8
16
16
8
54
8
31
8
8
0
16
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
8
0
0
0
16
8
0
8
0
16
8
8
0
31
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
8
0
0
8
8
8
0
8
0
0
16
16
8
% K
% Leu:
0
0
0
16
8
24
16
0
0
8
0
8
0
0
8
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
47
24
39
0
0
39
8
16
8
16
8
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
16
8
8
8
8
8
0
% Q
% Arg:
16
0
8
16
0
0
0
8
0
0
0
16
8
31
0
% R
% Ser:
0
0
0
24
8
0
0
39
0
0
0
0
47
16
0
% S
% Thr:
0
0
0
0
16
0
0
0
0
0
0
8
0
8
16
% T
% Val:
0
0
0
8
0
0
16
0
8
47
0
31
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _