Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF25 All Species: 10
Human Site: S284 Identified Species: 18.33
UniProt: Q96BH1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BH1 NP_071898.2 459 51219 S284 A V D V S K G S Q P P S T L A
Chimpanzee Pan troglodytes XP_001158338 459 51203 S284 A V D V S K G S Q P P S T L A
Rhesus Macaque Macaca mulatta XP_001090728 414 45939 V255 E L P T S S A V Q S T L P T P
Dog Lupus familis XP_536071 459 51107 S284 A V D A S R G S Q P P S A L A
Cat Felis silvestris
Mouse Mus musculus Q9QZR0 456 51208 P281 A V D V S R E P Q P P N A L S
Rat Rattus norvegicus NP_001012004 454 50810 P279 V V D V S R G P Q P P N T L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026430 410 46105 S251 G Q G R Q S C S S S Q E G A G
Frog Xenopus laevis NP_001092170 377 42394 Y218 Q K E L R Q I Y Q V Q L A K G
Zebra Danio Brachydanio rerio NP_957477 513 56750 G339 A P G G E R L G K H I Q S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610915 374 42153 E215 A P E F K V T E E L R Q M Q Q
Honey Bee Apis mellifera XP_624230 342 39095 N183 Q W Q Q D T T N K F Q A I C P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191589 366 41201 H207 P V C R K I F H S S D I E H V
Baker's Yeast Sacchar. cerevisiae Q03768 265 31012 V106 Y D D H G N K V L K K F E N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 84.3 89.1 N.A. 82.3 84.5 N.A. N.A. 20.9 38.3 35.4 N.A. 27.2 29.6 N.A. N.A.
Protein Similarity: 100 98.6 86 93.2 N.A. 87.3 89.1 N.A. N.A. 32.6 54.9 51.4 N.A. 43.3 43.3 N.A. N.A.
P-Site Identity: 100 100 13.3 80 N.A. 60 66.6 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 20 86.6 N.A. 80 86.6 N.A. N.A. 6.6 26.6 26.6 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. 38.1 32.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 0 8 0 0 8 0 0 0 0 8 24 8 24 % A
% Cys: 0 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % C
% Asp: 0 8 47 0 8 0 0 0 0 0 8 0 0 0 8 % D
% Glu: 8 0 16 0 8 0 8 8 8 0 0 8 16 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 8 0 8 0 0 0 % F
% Gly: 8 0 16 8 8 0 31 8 0 0 0 0 8 0 16 % G
% His: 0 0 0 8 0 0 0 8 0 8 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 8 8 8 0 0 % I
% Lys: 0 8 0 0 16 16 8 0 16 8 8 0 0 8 0 % K
% Leu: 0 8 0 8 0 0 8 0 8 8 0 16 0 39 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 16 0 8 0 % N
% Pro: 8 16 8 0 0 0 0 16 0 39 39 0 8 0 16 % P
% Gln: 16 8 8 8 8 8 0 0 54 0 24 16 0 8 8 % Q
% Arg: 0 0 0 16 8 31 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 47 16 0 31 16 24 0 24 8 8 16 % S
% Thr: 0 0 0 8 0 8 16 0 0 0 8 0 24 8 0 % T
% Val: 8 47 0 31 0 8 0 16 0 8 0 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _