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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
10.91
Human Site:
S391
Identified Species:
20
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
S391
D
L
K
P
E
P
H
S
Q
G
V
E
G
P
P
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
S391
D
L
K
P
E
P
H
S
Q
G
V
E
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
Q347
L
K
P
E
P
H
S
Q
G
V
E
G
P
P
Q
Dog
Lupus familis
XP_536071
459
51107
S391
D
L
K
P
E
P
C
S
Q
G
V
E
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
N388
D
L
K
A
E
P
R
N
K
G
L
T
G
H
P
Rat
Rattus norvegicus
NP_001012004
454
50810
N386
D
L
K
A
E
P
R
N
K
G
L
T
G
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
E343
G
A
E
A
Q
S
R
E
K
E
N
L
A
F
N
Frog
Xenopus laevis
NP_001092170
377
42394
M310
D
H
N
A
N
S
H
M
Y
H
G
R
G
R
K
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
S441
G
R
G
D
K
R
G
S
R
G
S
A
R
H
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
Y307
P
E
P
T
N
N
N
Y
H
H
N
R
R
H
Y
Honey Bee
Apis mellifera
XP_624230
342
39095
S275
G
P
N
P
P
G
T
S
V
N
T
Y
S
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
Q299
E
E
E
A
G
E
S
Q
E
Q
G
E
E
E
P
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
E198
V
T
R
E
S
Y
L
E
W
R
S
K
F
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
53.3
53.3
N.A.
N.A.
0
20
13.3
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
6.6
93.3
N.A.
73.3
73.3
N.A.
N.A.
20
20
26.6
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
39
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
47
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
16
16
16
39
8
0
16
8
8
8
31
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
24
0
8
0
8
8
8
0
8
47
16
8
47
0
0
% G
% His:
0
8
0
0
0
8
24
0
8
16
0
0
0
31
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
39
0
8
0
0
0
24
0
0
8
0
0
8
% K
% Leu:
8
39
0
0
0
0
8
0
0
0
16
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
16
8
8
16
0
8
16
0
0
0
8
% N
% Pro:
8
8
16
31
16
39
0
0
0
0
0
0
8
31
47
% P
% Gln:
0
0
0
0
8
0
0
16
24
8
0
0
0
0
24
% Q
% Arg:
0
8
8
0
0
8
24
0
8
8
0
16
16
16
0
% R
% Ser:
0
0
0
0
8
16
16
39
0
0
16
0
8
0
0
% S
% Thr:
0
8
0
8
0
0
8
0
0
0
8
16
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
8
24
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
8
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _