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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
13.64
Human Site:
S405
Identified Species:
25
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
S405
P
Q
E
K
G
P
G
S
W
Q
G
P
P
P
R
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
S405
P
Q
E
K
G
P
G
S
W
Q
G
P
P
P
R
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
W361
Q
E
K
G
P
G
S
W
Q
G
P
P
P
R
R
Dog
Lupus familis
XP_536071
459
51107
N405
P
Q
E
K
G
P
G
N
W
Q
G
P
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
S402
P
Q
E
K
G
P
G
S
W
Q
G
P
S
A
R
Rat
Rattus norvegicus
NP_001012004
454
50810
S400
P
Q
E
K
G
P
G
S
W
Q
G
P
S
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
A357
N
R
S
E
H
R
A
A
P
G
C
Q
G
H
H
Frog
Xenopus laevis
NP_001092170
377
42394
P324
K
P
H
G
R
G
R
P
E
R
Y
D
L
S
G
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
N455
H
G
H
W
Q
D
R
N
Y
K
G
P
G
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
H321
Y
R
G
G
R
R
H
H
H
H
H
Q
H
G
H
Honey Bee
Apis mellifera
XP_624230
342
39095
K289
Q
P
V
N
Q
M
S
K
Q
S
S
H
Q
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
T313
P
K
E
A
E
S
E
T
N
S
S
S
S
T
N
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
R212
Q
E
L
K
L
D
E
R
D
Q
V
R
R
M
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
86.6
86.6
N.A.
N.A.
0
0
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
86.6
N.A.
N.A.
20
6.6
33.3
N.A.
6.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
8
0
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
16
47
8
8
0
16
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
24
39
16
39
0
0
16
47
0
16
8
8
% G
% His:
8
0
16
0
8
0
8
8
8
8
8
8
8
16
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
47
0
0
0
8
0
8
0
0
0
0
8
% K
% Leu:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
8
0
0
0
16
8
0
0
0
0
0
8
% N
% Pro:
47
16
0
0
8
39
0
8
8
0
8
54
31
24
0
% P
% Gln:
24
39
0
0
16
0
0
0
16
47
0
16
8
0
8
% Q
% Arg:
0
16
0
0
16
16
16
8
0
8
0
8
8
8
47
% R
% Ser:
0
0
8
0
0
8
16
31
0
16
16
8
24
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
8
39
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _