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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
9.09
Human Site:
T126
Identified Species:
16.67
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
T126
E
K
G
K
E
I
L
T
D
N
N
I
P
H
G
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
T126
E
K
G
K
E
I
L
T
D
N
N
I
P
H
G
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
F112
K
T
P
C
Y
H
Y
F
H
C
H
C
L
A
R
Dog
Lupus familis
XP_536071
459
51107
T126
E
K
G
K
E
I
L
T
D
N
N
I
P
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
D126
K
G
K
E
I
L
T
D
N
N
I
P
H
G
Q
Rat
Rattus norvegicus
NP_001012004
454
50810
D126
K
G
K
E
I
L
T
D
N
N
I
P
H
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
V108
P
V
C
R
E
T
L
V
Y
D
L
C
A
L
K
Frog
Xenopus laevis
NP_001092170
377
42394
V75
A
E
V
P
E
I
S
V
K
N
P
R
G
L
C
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
L162
I
T
H
S
E
M
E
L
K
D
R
E
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
R72
S
P
T
F
K
L
L
R
P
R
G
L
D
D
A
Honey Bee
Apis mellifera
XP_624230
342
39095
E40
R
G
E
P
E
Y
I
E
T
V
L
F
P
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
P64
G
S
K
Y
P
D
E
P
P
R
I
S
L
I
E
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
6.6
6.6
N.A.
N.A.
13.3
20
6.6
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
33.3
33.3
N.A.
N.A.
26.6
26.6
20
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
8
8
0
0
0
0
0
8
0
16
0
0
8
% C
% Asp:
0
0
0
0
0
8
0
16
24
16
0
0
8
8
0
% D
% Glu:
24
8
8
16
54
0
16
8
0
0
0
8
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
8
24
24
0
0
0
0
0
0
0
8
0
8
16
24
% G
% His:
0
0
8
0
0
8
0
0
8
0
8
0
16
24
0
% H
% Ile:
8
0
0
0
16
31
8
0
0
0
24
24
0
8
0
% I
% Lys:
24
24
24
24
8
0
0
0
16
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
24
39
8
0
0
16
8
16
16
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
16
47
24
0
0
0
0
% N
% Pro:
8
8
8
16
8
0
0
8
16
0
8
16
31
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% Q
% Arg:
8
0
0
8
0
0
0
8
0
16
8
8
8
0
8
% R
% Ser:
8
8
0
8
0
0
8
0
0
0
0
8
0
8
0
% S
% Thr:
0
16
8
0
0
8
16
24
8
0
0
0
0
0
8
% T
% Val:
0
8
8
0
0
0
0
16
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _