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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
9.7
Human Site:
T289
Identified Species:
17.78
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
T289
K
G
S
Q
P
P
S
T
L
A
A
E
L
S
T
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
T289
K
G
S
Q
P
P
S
T
L
A
A
E
L
S
T
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
P260
S
A
V
Q
S
T
L
P
T
P
L
P
V
A
T
Dog
Lupus familis
XP_536071
459
51107
A289
R
G
S
Q
P
P
S
A
L
A
S
E
L
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
A286
R
E
P
Q
P
P
N
A
L
S
A
E
Q
S
T
Rat
Rattus norvegicus
NP_001012004
454
50810
T284
R
G
P
Q
P
P
N
T
L
S
A
E
Q
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
G256
S
C
S
S
S
Q
E
G
A
G
E
A
C
H
L
Frog
Xenopus laevis
NP_001092170
377
42394
A223
Q
I
Y
Q
V
Q
L
A
K
G
G
I
I
D
I
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
S344
R
L
G
K
H
I
Q
S
S
D
K
I
N
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
M220
V
T
E
E
L
R
Q
M
Q
Q
R
M
S
E
L
Honey Bee
Apis mellifera
XP_624230
342
39095
I188
T
T
N
K
F
Q
A
I
C
P
V
C
R
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
E212
I
F
H
S
S
D
I
E
H
V
L
D
L
V
G
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
E111
N
K
V
L
K
K
F
E
N
L
P
D
L
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
53.3
66.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
73.3
86.6
N.A.
N.A.
6.6
20
26.6
N.A.
6.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
24
8
24
31
8
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
8
0
0
8
8
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
16
0
8
0
% D
% Glu:
0
8
8
8
0
0
8
16
0
0
8
39
0
16
0
% E
% Phe:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
31
8
0
0
0
0
8
0
16
8
0
0
0
8
% G
% His:
0
0
8
0
8
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
0
8
8
8
0
0
0
16
8
8
8
% I
% Lys:
16
8
0
16
8
8
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
8
0
8
8
0
16
0
39
8
16
0
39
0
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
0
0
16
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
16
0
39
39
0
8
0
16
8
8
0
0
0
% P
% Gln:
8
0
0
54
0
24
16
0
8
8
0
0
16
0
0
% Q
% Arg:
31
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% R
% Ser:
16
0
31
16
24
0
24
8
8
16
8
0
8
47
16
% S
% Thr:
8
16
0
0
0
8
0
24
8
0
0
0
0
0
47
% T
% Val:
8
0
16
0
8
0
0
0
0
8
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _