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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF25 All Species: 8.48
Human Site: T369 Identified Species: 15.56
UniProt: Q96BH1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BH1 NP_071898.2 459 51219 T369 A P K G T R D T Q E L P P P E
Chimpanzee Pan troglodytes XP_001158338 459 51203 T369 A P K G T R D T Q E L P P P E
Rhesus Macaque Macaca mulatta XP_001090728 414 45939 G332 Q E L P P P E G P L K E P V D
Dog Lupus familis XP_536071 459 51107 T369 A H K G T S D T Q E L P P P E
Cat Felis silvestris
Mouse Mus musculus Q9QZR0 456 51208 I366 T P K G T S E I H E L P P P E
Rat Rattus norvegicus NP_001012004 454 50810 I364 A P K G T S E I Q E L P P P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026430 410 46105 M328 L K E E H H N M E R W T P E Q
Frog Xenopus laevis NP_001092170 377 42394 Q295 Q R Q G Y R N Q H Y R P V H T
Zebra Danio Brachydanio rerio NP_957477 513 56750 I422 S K E V T Q T I L Q E G H P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610915 374 42153 V292 S S T F A P V V Q E T H R I M
Honey Bee Apis mellifera XP_624230 342 39095 D260 K T L V R T E D E S G A T T E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191589 366 41201 H284 M Y L P P P A H A S T S R N E
Baker's Yeast Sacchar. cerevisiae Q03768 265 31012 Q183 Q E R E K K E Q A K F H G T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 84.3 89.1 N.A. 82.3 84.5 N.A. N.A. 20.9 38.3 35.4 N.A. 27.2 29.6 N.A. N.A.
Protein Similarity: 100 98.6 86 93.2 N.A. 87.3 89.1 N.A. N.A. 32.6 54.9 51.4 N.A. 43.3 43.3 N.A. N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 66.6 80 N.A. N.A. 6.6 20 20 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 100 20 86.6 N.A. 73.3 86.6 N.A. N.A. 33.3 33.3 46.6 N.A. 20 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. 38.1 32.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 0 0 0 8 0 8 0 16 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 24 8 0 0 0 0 0 0 8 % D
% Glu: 0 16 16 16 0 0 39 0 16 47 8 8 0 8 62 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 47 0 0 0 8 0 0 8 8 8 0 0 % G
% His: 0 8 0 0 8 8 0 8 16 0 0 16 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 24 0 0 0 0 0 8 0 % I
% Lys: 8 16 39 0 8 8 0 0 0 8 8 0 0 0 8 % K
% Leu: 8 0 24 0 0 0 0 0 8 8 39 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 16 0 0 0 0 0 0 8 0 % N
% Pro: 0 31 0 16 16 24 0 0 8 0 0 47 54 47 0 % P
% Gln: 24 0 8 0 0 8 0 16 39 8 0 0 0 0 8 % Q
% Arg: 0 8 8 0 8 24 0 0 0 8 8 0 16 0 0 % R
% Ser: 16 8 0 0 0 24 0 0 0 16 0 8 0 0 0 % S
% Thr: 8 8 8 0 47 8 8 24 0 0 16 8 8 16 8 % T
% Val: 0 0 0 16 0 0 8 8 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _