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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
19.09
Human Site:
Y225
Identified Species:
35
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
Y225
P
Q
Q
P
M
E
L
Y
Q
P
S
A
E
S
L
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
Y225
P
Q
Q
P
M
E
L
Y
Q
P
S
V
E
S
L
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
Q200
R
K
R
L
Y
Q
R
Q
Q
E
R
G
G
I
I
Dog
Lupus familis
XP_536071
459
51107
Y225
P
Q
Q
P
M
E
L
Y
Q
P
S
A
E
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
Y222
P
Q
Q
P
M
E
L
Y
Q
P
S
A
E
S
L
Rat
Rattus norvegicus
NP_001012004
454
50810
Y220
P
Q
Q
P
M
E
L
Y
Q
P
S
A
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
Q196
A
S
N
V
D
A
P
Q
A
P
C
Q
A
S
A
Frog
Xenopus laevis
NP_001092170
377
42394
E163
R
Y
A
E
H
S
T
E
Q
K
R
S
E
E
L
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
P281
A
E
S
T
Q
S
L
P
S
S
S
P
D
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
Y160
L
N
A
L
R
R
N
Y
Q
E
E
F
D
K
L
Honey Bee
Apis mellifera
XP_624230
342
39095
Q128
R
S
N
L
P
T
D
Q
C
A
I
C
L
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
C152
S
C
F
H
C
F
H
C
E
C
I
I
R
W
W
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
L51
T
G
D
S
T
S
V
L
T
K
E
H
T
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
100
N.A.
100
100
N.A.
N.A.
13.3
20
20
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
93.3
33.3
100
N.A.
100
100
N.A.
N.A.
13.3
26.6
33.3
N.A.
26.6
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
0
0
8
0
0
8
8
0
31
8
0
8
% A
% Cys:
0
8
0
0
8
0
0
8
8
8
8
8
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
0
0
0
16
0
0
% D
% Glu:
0
8
0
8
0
39
0
8
8
16
16
0
47
8
0
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
8
% G
% His:
0
0
0
8
8
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
8
0
16
16
% I
% Lys:
0
8
0
0
0
0
0
0
0
16
0
0
0
8
0
% K
% Leu:
8
0
0
24
0
0
47
8
0
0
0
0
8
0
54
% L
% Met:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
16
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
39
0
0
39
8
0
8
8
0
47
0
8
0
0
0
% P
% Gln:
0
39
39
0
8
8
0
24
62
0
0
8
0
0
0
% Q
% Arg:
24
0
8
0
8
8
8
0
0
0
16
0
8
0
0
% R
% Ser:
8
16
8
8
0
24
0
0
8
8
47
8
0
54
0
% S
% Thr:
8
0
0
8
8
8
8
0
8
0
0
0
8
0
8
% T
% Val:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
8
0
0
8
0
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _