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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
16.36
Human Site:
Y442
Identified Species:
30
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
Y442
L
P
R
G
Q
G
A
Y
R
P
G
T
R
R
E
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
Y442
L
P
R
G
Q
G
A
Y
R
P
G
T
R
R
E
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
R398
P
R
G
Q
G
A
Y
R
P
G
T
R
R
E
P
Dog
Lupus familis
XP_536071
459
51107
F442
L
P
R
G
R
G
A
F
R
P
G
T
R
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
Y439
L
P
R
G
Q
G
A
Y
R
S
G
T
R
R
E
Rat
Rattus norvegicus
NP_001012004
454
50810
Y437
L
P
R
G
Q
G
A
Y
R
S
G
T
R
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
R394
P
R
G
R
G
V
F
R
P
S
G
R
R
E
A
Frog
Xenopus laevis
NP_001092170
377
42394
Q361
F
R
S
G
A
M
V
Q
L
P
P
R
G
R
G
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
Y492
G
H
R
G
G
G
A
Y
R
G
G
G
R
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
T358
S
T
S
N
A
V
N
T
N
S
K
Q
A
K
A
Honey Bee
Apis mellifera
XP_624230
342
39095
H326
N
R
G
R
G
R
A
H
Y
R
R
Q
F
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
P350
R
K
P
N
S
Q
D
P
R
K
P
T
R
Q
W
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
S249
Y
M
E
E
D
D
A
S
V
D
D
V
A
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
N.A.
13.3
20
53.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
20
53.3
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
62
0
0
0
0
0
16
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
8
0
0
8
8
0
0
8
0
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
0
0
0
16
39
% E
% Phe:
8
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% F
% Gly:
8
0
24
54
31
47
0
0
0
16
54
8
8
8
16
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
8
0
0
16
0
% K
% Leu:
39
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
16
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
16
39
8
0
0
0
0
8
16
31
16
0
0
0
8
% P
% Gln:
0
0
0
8
31
8
0
8
0
0
0
16
0
8
0
% Q
% Arg:
8
31
47
16
8
8
0
16
54
8
8
24
70
47
8
% R
% Ser:
8
0
16
0
8
0
0
8
0
31
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
8
47
0
0
0
% T
% Val:
0
0
0
0
0
16
8
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
0
8
39
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _