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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF25
All Species:
10.91
Human Site:
Y74
Identified Species:
20
UniProt:
Q96BH1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BH1
NP_071898.2
459
51219
Y74
V
L
Q
V
P
A
E
Y
P
H
E
V
P
Q
I
Chimpanzee
Pan troglodytes
XP_001158338
459
51203
Y74
V
L
Q
V
P
A
E
Y
P
H
E
V
P
Q
I
Rhesus Macaque
Macaca mulatta
XP_001090728
414
45939
G60
L
T
S
A
G
P
C
G
K
A
G
L
G
A
A
Dog
Lupus familis
XP_536071
459
51107
Y74
V
L
Q
V
P
T
Q
Y
P
N
E
V
P
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR0
456
51208
P74
L
R
I
P
V
Q
Y
P
H
E
V
P
Q
I
S
Rat
Rattus norvegicus
NP_001012004
454
50810
P74
L
Q
V
P
V
Q
Y
P
H
E
V
P
Q
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026430
410
46105
Q56
R
E
A
F
T
K
T
Q
C
Y
H
Y
F
H
S
Frog
Xenopus laevis
NP_001092170
377
42394
Y23
L
Q
V
L
E
S
I
Y
P
G
E
L
Q
I
S
Zebra Danio
Brachydanio rerio
NP_957477
513
56750
A110
L
Y
Q
L
I
E
R
A
K
E
I
L
T
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610915
374
42153
C20
A
I
L
M
D
D
V
C
I
K
R
T
P
S
G
Honey Bee
Apis mellifera
XP_624230
342
39095
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191589
366
41201
A12
E
V
A
M
E
V
E
A
L
E
A
V
Y
S
E
Baker's Yeast
Sacchar. cerevisiae
Q03768
265
31012
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
84.3
89.1
N.A.
82.3
84.5
N.A.
N.A.
20.9
38.3
35.4
N.A.
27.2
29.6
N.A.
N.A.
Protein Similarity:
100
98.6
86
93.2
N.A.
87.3
89.1
N.A.
N.A.
32.6
54.9
51.4
N.A.
43.3
43.3
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
0
0
N.A.
N.A.
0
20
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
46.6
26.6
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
32.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
16
0
16
0
8
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
16
8
24
0
0
31
31
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
8
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
16
16
8
0
0
8
0
% H
% Ile:
0
8
8
0
8
0
8
0
8
0
8
0
0
24
24
% I
% Lys:
0
0
0
0
0
8
0
0
16
8
0
0
0
0
0
% K
% Leu:
39
24
8
16
0
0
0
0
8
0
0
24
0
0
0
% L
% Met:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
16
24
8
0
16
31
0
0
16
31
0
0
% P
% Gln:
0
16
31
0
0
16
8
8
0
0
0
0
24
24
0
% Q
% Arg:
8
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
0
0
0
0
0
0
16
39
% S
% Thr:
0
8
0
0
8
8
8
0
0
0
0
8
8
0
0
% T
% Val:
24
8
16
24
16
8
8
0
0
0
16
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
16
31
0
8
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _