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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A18
All Species:
10
Human Site:
S205
Identified Species:
24.44
UniProt:
Q96BI1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BI1
NP_002546.3
424
44846
S205
S
F
T
C
I
P
A
S
T
K
G
A
K
T
D
Chimpanzee
Pan troglodytes
XP_508226
424
44754
S205
X
X
X
X
X
P
A
S
G
K
G
A
K
T
D
Rhesus Macaque
Macaca mulatta
XP_001117317
316
33196
S111
L
L
L
A
A
A
S
S
P
A
L
P
G
V
Y
Dog
Lupus familis
XP_533204
517
54564
S298
S
F
T
C
I
P
T
S
T
K
G
V
S
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q78KK3
406
42994
T189
S
F
T
C
V
P
A
T
T
K
E
A
S
V
Q
Rat
Rattus norvegicus
Q6AY78
404
43011
C185
G
A
V
L
S
F
T
C
I
P
V
T
T
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507546
296
31156
G91
Q
G
R
S
T
P
G
G
G
G
G
G
G
V
F
Chicken
Gallus gallus
XP_421021
424
45491
V205
I
N
T
V
L
S
V
V
W
I
P
S
P
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501557
415
45796
K195
L
E
T
C
I
E
K
K
S
Y
E
H
E
I
S
Sea Urchin
Strong. purpuratus
XP_001201832
387
40642
F180
R
S
S
P
G
A
A
F
F
L
S
V
N
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
71.2
55.1
N.A.
76.4
75.2
N.A.
34.6
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
29.9
Protein Similarity:
100
97.4
72.4
64.8
N.A.
84.9
83.4
N.A.
48.8
71.6
N.A.
N.A.
N.A.
N.A.
N.A.
45.5
47.8
P-Site Identity:
100
60
6.6
66.6
N.A.
60
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
60
13.3
73.3
N.A.
73.3
6.6
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
20
40
0
0
10
0
30
0
10
0
% A
% Cys:
0
0
0
40
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
20
0
10
0
10
% E
% Phe:
0
30
0
0
0
10
0
10
10
0
0
0
0
0
10
% F
% Gly:
10
10
0
0
10
0
10
10
20
10
40
10
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
30
0
0
0
10
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
40
0
0
20
10
10
% K
% Leu:
20
10
10
10
10
0
0
0
0
10
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
10
0
50
0
0
10
10
10
10
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
30
10
10
10
10
10
10
40
10
0
10
10
20
10
10
% S
% Thr:
0
0
50
0
10
0
20
10
30
0
0
10
10
20
0
% T
% Val:
0
0
10
10
10
0
10
10
0
0
10
20
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _