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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC22A18 All Species: 5.45
Human Site: T211 Identified Species: 13.33
UniProt: Q96BI1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BI1 NP_002546.3 424 44846 T211 A S T K G A K T D A Q A P L P
Chimpanzee Pan troglodytes XP_508226 424 44754 T211 A S G K G A K T D A Q A P L P
Rhesus Macaque Macaca mulatta XP_001117317 316 33196 V117 S S P A L P G V Y L L F A S R
Dog Lupus familis XP_533204 517 54564 A304 T S T K G V S A N A Q A T P P
Cat Felis silvestris
Mouse Mus musculus Q78KK3 406 42994 V195 A T T K E A S V Q S A P Q G G
Rat Rattus norvegicus Q6AY78 404 43011 K191 T C I P V T T K E A S V Q S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507546 296 31156 V97 G G G G G G G V F S L K E T W
Chicken Gallus gallus XP_421021 424 45491 S211 V V W I P S P S K P K S E H R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501557 415 45796 I201 K K S Y E H E I S T D N A N G
Sea Urchin Strong. purpuratus XP_001201832 387 40642 L186 A F F L S V N L L A G L P S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 71.2 55.1 N.A. 76.4 75.2 N.A. 34.6 53.7 N.A. N.A. N.A. N.A. N.A. 28.7 29.9
Protein Similarity: 100 97.4 72.4 64.8 N.A. 84.9 83.4 N.A. 48.8 71.6 N.A. N.A. N.A. N.A. N.A. 45.5 47.8
P-Site Identity: 100 93.3 6.6 53.3 N.A. 26.6 6.6 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. 0 20
P-Site Similarity: 100 93.3 13.3 60 N.A. 40 13.3 N.A. 13.3 26.6 N.A. N.A. N.A. N.A. N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 10 0 30 0 10 0 50 10 30 20 0 20 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 20 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 20 0 10 0 10 0 0 0 20 0 0 % E
% Phe: 0 10 10 0 0 0 0 0 10 0 0 10 0 0 0 % F
% Gly: 10 10 20 10 40 10 20 0 0 0 10 0 0 10 20 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 10 10 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 10 0 40 0 0 20 10 10 0 10 10 0 0 0 % K
% Leu: 0 0 0 10 10 0 0 10 10 10 20 10 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 0 0 10 0 10 0 % N
% Pro: 0 0 10 10 10 10 10 0 0 10 0 10 30 10 30 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 30 0 20 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % R
% Ser: 10 40 10 0 10 10 20 10 10 20 10 10 0 30 0 % S
% Thr: 20 10 30 0 0 10 10 20 0 10 0 0 10 10 0 % T
% Val: 10 10 0 0 10 20 0 30 0 0 0 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _