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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1A
All Species:
10.91
Human Site:
S103
Identified Species:
21.82
UniProt:
Q96BI3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BI3
NP_001071096.1
265
28996
S103
K
A
D
E
G
L
A
S
L
S
E
D
G
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099903
222
24392
R66
V
T
D
R
S
D
A
R
L
Q
Y
G
L
L
I
Dog
Lupus familis
XP_540299
265
28985
S103
K
A
D
E
G
L
A
S
L
S
E
D
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVF7
265
28967
S103
K
A
D
E
G
L
A
S
L
S
E
D
G
R
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
M69
K
K
A
N
K
G
L
M
T
I
S
Q
E
E
T
Chicken
Gallus gallus
XP_001233302
256
28091
E99
K
L
L
R
K
A
I
E
G
L
V
A
L
S
E
Frog
Xenopus laevis
NP_001089056
247
26905
Y91
E
T
F
R
Y
A
Y
Y
R
L
L
K
K
A
D
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
E99
R
L
L
K
K
A
N
E
G
L
L
A
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
R82
A
F
R
Y
I
I
Y
R
I
L
R
S
T
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45876
308
33529
S103
I
T
R
Q
G
Q
I
S
V
A
P
G
V
S
D
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
A103
N
Q
T
T
P
E
Q
A
Q
Q
Q
A
Q
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
D94
K
V
Y
K
R
L
E
D
V
L
D
S
F
A
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.4
99.2
N.A.
99.2
N.A.
N.A.
55.8
60.7
69.4
61.1
N.A.
40
N.A.
29.5
40.7
Protein Similarity:
100
N.A.
83.7
99.2
N.A.
99.6
N.A.
N.A.
71.6
75
83
79.2
N.A.
60.7
N.A.
48.7
56.2
P-Site Identity:
100
N.A.
20
100
N.A.
100
N.A.
N.A.
6.6
6.6
0
0
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
N.A.
N.A.
13.3
6.6
6.6
13.3
N.A.
13.3
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
9
0
0
25
34
9
0
9
0
25
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
9
0
9
0
0
9
25
0
0
25
% D
% Glu:
9
0
0
25
0
9
9
17
0
0
25
0
9
17
9
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
34
9
0
0
17
0
0
17
25
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
9
17
0
9
9
0
0
0
0
9
% I
% Lys:
50
9
0
17
25
0
0
0
0
0
0
9
9
0
0
% K
% Leu:
0
17
17
0
0
34
9
0
34
42
17
0
25
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
9
0
9
0
9
9
0
9
17
9
9
9
0
17
% Q
% Arg:
9
0
17
25
9
0
0
17
9
0
9
0
0
25
0
% R
% Ser:
0
0
0
0
9
0
0
34
0
25
9
17
0
25
34
% S
% Thr:
0
25
9
9
0
0
0
0
9
0
0
0
9
0
9
% T
% Val:
9
9
0
0
0
0
0
0
17
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
9
0
17
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _