KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1A
All Species:
10.61
Human Site:
S110
Identified Species:
21.21
UniProt:
Q96BI3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BI3
NP_001071096.1
265
28996
S110
S
L
S
E
D
G
R
S
P
I
S
I
R
Q
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099903
222
24392
I73
R
L
Q
Y
G
L
L
I
F
G
A
A
V
S
V
Dog
Lupus familis
XP_540299
265
28985
S110
S
L
S
E
D
G
R
S
P
I
S
I
R
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVF7
265
28967
S110
S
L
S
E
D
G
R
S
P
I
S
I
R
Q
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
T76
M
T
I
S
Q
E
E
T
V
P
I
S
V
R
Q
Chicken
Gallus gallus
XP_001233302
256
28091
E106
E
G
L
V
A
L
S
E
D
G
C
S
P
I
S
Frog
Xenopus laevis
NP_001089056
247
26905
D98
Y
R
L
L
K
K
A
D
E
G
L
A
T
I
S
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
Q106
E
G
L
L
A
L
S
Q
E
D
T
M
P
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
Q89
R
I
L
R
S
T
E
Q
G
L
H
A
V
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45876
308
33529
D110
S
V
A
P
G
V
S
D
L
H
N
A
R
H
M
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
S110
A
Q
Q
Q
A
Q
N
S
N
G
D
S
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
D101
D
V
L
D
S
F
A
D
R
I
S
R
P
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.4
99.2
N.A.
99.2
N.A.
N.A.
55.8
60.7
69.4
61.1
N.A.
40
N.A.
29.5
40.7
Protein Similarity:
100
N.A.
83.7
99.2
N.A.
99.6
N.A.
N.A.
71.6
75
83
79.2
N.A.
60.7
N.A.
48.7
56.2
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
N.A.
N.A.
0
0
0
0
N.A.
0
N.A.
20
6.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
N.A.
N.A.
13.3
0
0
13.3
N.A.
13.3
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
25
0
17
0
0
0
9
34
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
9
25
0
0
25
9
9
9
0
0
0
9
% D
% Glu:
17
0
0
25
0
9
17
9
17
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
17
25
0
0
9
34
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% H
% Ile:
0
9
9
0
0
0
0
9
0
34
9
25
0
25
0
% I
% Lys:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
34
42
17
0
25
9
0
9
9
9
0
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
34
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
25
9
0
0
25
0
0
% P
% Gln:
0
9
17
9
9
9
0
17
0
0
0
0
0
25
9
% Q
% Arg:
17
9
0
9
0
0
25
0
9
0
0
9
34
17
0
% R
% Ser:
34
0
25
9
17
0
25
34
0
0
34
25
0
17
25
% S
% Thr:
0
9
0
0
0
9
0
9
0
0
9
0
17
0
0
% T
% Val:
0
17
0
9
0
9
0
0
9
0
0
0
25
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _