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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1A
All Species:
10.3
Human Site:
S242
Identified Species:
20.61
UniProt:
Q96BI3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BI3
NP_001071096.1
265
28996
S242
S
L
R
S
I
Q
R
S
L
L
C
R
R
Q
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099903
222
24392
G200
Y
A
V
T
V
S
M
G
L
W
A
F
I
T
A
Dog
Lupus familis
XP_540299
265
28985
S242
S
F
R
S
I
Q
R
S
L
S
C
R
R
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVF7
265
28967
S242
S
L
R
S
I
Q
R
S
L
S
C
R
R
Q
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
L203
F
F
T
A
G
G
S
L
R
N
L
K
R
C
L
Chicken
Gallus gallus
XP_001233302
256
28091
G233
V
W
A
Y
M
L
S
G
G
S
V
Q
N
L
R
Frog
Xenopus laevis
NP_001089056
247
26905
A225
Y
I
I
T
L
G
M
A
L
W
A
F
V
A
A
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
L236
Y
L
C
A
G
G
S
L
R
N
L
K
L
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
T216
N
Y
L
V
T
I
L
T
G
V
L
A
F
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45876
308
33529
T254
C
N
V
I
M
G
G
T
I
S
S
F
V
N
G
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
F237
A
V
M
T
L
F
A
F
F
I
A
G
G
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
L228
Y
L
V
A
S
L
T
L
V
H
C
G
K
M
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.4
99.2
N.A.
99.2
N.A.
N.A.
55.8
60.7
69.4
61.1
N.A.
40
N.A.
29.5
40.7
Protein Similarity:
100
N.A.
83.7
99.2
N.A.
99.6
N.A.
N.A.
71.6
75
83
79.2
N.A.
60.7
N.A.
48.7
56.2
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
93.3
N.A.
N.A.
6.6
0
6.6
6.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
N.A.
20
86.6
N.A.
93.3
N.A.
N.A.
20
13.3
33.3
20
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
25
0
0
9
9
0
0
25
9
0
9
17
% A
% Cys:
9
0
9
0
0
0
0
0
0
0
34
0
0
17
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% E
% Phe:
9
17
0
0
0
9
0
9
9
0
0
25
9
0
0
% F
% Gly:
0
0
0
0
17
34
9
17
17
0
0
17
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
9
9
25
9
0
0
9
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% K
% Leu:
0
34
9
0
17
17
9
25
42
9
25
0
9
9
17
% L
% Met:
0
0
9
0
17
0
17
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
17
0
0
9
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
25
0
0
0
0
0
9
0
25
0
% Q
% Arg:
0
0
25
0
0
0
25
0
17
0
0
25
34
9
9
% R
% Ser:
25
0
0
25
9
9
25
25
0
34
9
0
0
9
9
% S
% Thr:
0
0
9
25
9
0
9
17
0
0
0
0
0
9
0
% T
% Val:
9
9
25
9
9
0
0
0
9
9
9
0
17
0
17
% V
% Trp:
0
9
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
34
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _