KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APH1A
All Species:
10.3
Human Site:
Y256
Identified Species:
20.61
UniProt:
Q96BI3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BI3
NP_001071096.1
265
28996
Y256
E
D
S
R
V
M
V
Y
S
A
L
R
I
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099903
222
24392
I214
A
G
G
S
L
R
S
I
Q
R
S
L
L
C
K
Dog
Lupus familis
XP_540299
265
28985
Y256
E
D
S
R
V
M
V
Y
S
A
L
R
I
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVF7
265
28967
Y256
E
D
S
R
V
M
V
Y
S
A
L
R
I
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514807
225
24964
F217
L
M
C
R
D
K
D
F
L
L
S
N
Q
R
A
Chicken
Gallus gallus
XP_001233302
256
28091
Q247
R
R
F
L
L
C
A
Q
S
E
A
S
P
Q
P
Frog
Xenopus laevis
NP_001089056
247
26905
I239
A
G
G
N
Y
R
N
I
R
K
C
L
A
C
A
Zebra Danio
Brachydanio rerio
Q8JHE9
258
28628
F250
L
T
C
K
D
K
D
F
L
L
A
N
H
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG2
238
26419
S230
V
A
G
G
T
S
R
S
F
R
K
F
I
T
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45876
308
33529
D268
G
I
G
Q
S
I
T
D
A
V
T
L
K
Q
V
Sea Urchin
Strong. purpuratus
XP_783542
260
29305
F251
S
R
G
I
K
Q
A
F
S
L
N
R
S
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L9G7
250
27517
S242
V
W
Q
R
L
L
E
S
R
N
Q
S
S
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.4
99.2
N.A.
99.2
N.A.
N.A.
55.8
60.7
69.4
61.1
N.A.
40
N.A.
29.5
40.7
Protein Similarity:
100
N.A.
83.7
99.2
N.A.
99.6
N.A.
N.A.
71.6
75
83
79.2
N.A.
60.7
N.A.
48.7
56.2
P-Site Identity:
100
N.A.
0
100
N.A.
100
N.A.
N.A.
6.6
13.3
0
6.6
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
N.A.
N.A.
13.3
20
0
20
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
0
17
0
9
25
17
0
9
9
17
% A
% Cys:
0
0
17
0
0
9
0
0
0
0
9
0
0
17
9
% C
% Asp:
0
25
0
0
17
0
17
9
0
0
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
25
9
0
0
9
0
0
0
% F
% Gly:
9
17
42
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
0
9
0
9
0
17
0
0
0
0
34
0
0
% I
% Lys:
0
0
0
9
9
17
0
0
0
9
9
0
9
0
9
% K
% Leu:
17
0
0
9
25
9
0
0
17
25
25
25
9
0
0
% L
% Met:
0
9
0
0
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
9
9
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
25
42
% P
% Gln:
0
0
9
9
0
9
0
9
9
0
9
0
9
17
0
% Q
% Arg:
9
17
0
42
0
17
9
0
17
17
0
34
0
25
0
% R
% Ser:
9
0
25
9
9
9
9
17
42
0
17
17
17
0
9
% S
% Thr:
0
9
0
0
9
0
9
0
0
0
9
0
0
9
0
% T
% Val:
17
0
0
0
25
0
25
0
0
9
0
0
0
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
25
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _