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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINX1 All Species: 19.09
Human Site: S161 Identified Species: 35
UniProt: Q96BK5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BK5 NP_060354.4 328 37035 S161 K T P E G D A S P S T P E E N
Chimpanzee Pan troglodytes XP_519603 333 37605 S161 K T P E G D A S P S T S D E N
Rhesus Macaque Macaca mulatta XP_001089816 328 36769 S161 K T P E G D A S P S T P D E N
Dog Lupus familis XP_849859 314 35718 S161 K T P E D D S S P A T P D G N
Cat Felis silvestris
Mouse Mus musculus Q9CZX5 332 37202 S161 K L A Q D G C S N S S A D E V
Rat Rattus norvegicus A4L691 331 36692 S161 K L A Q D G C S N S T A D E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420036 356 40488 T161 M K T Q D E A T D A E S Q E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013283 355 40546 G159 E T K D Q D E G S S G S D S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611495 726 82612 P185 D V E R Y P E P V L A V Q P E
Honey Bee Apis mellifera XP_391986 378 43625 D162 I N N N N S K D D N S S V G I
Nematode Worm Caenorhab. elegans NP_495955 339 39018 I165 S D N A E E K I E E K T E N S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53335 271 31293 K121 K Q K I I D G K W G I H F V K
Red Bread Mold Neurospora crassa Q7SHT5 369 41722 E162 D T V D Q Q V E T V P S Q D T
Conservation
Percent
Protein Identity: 100 96.6 94.2 75.9 N.A. 72.8 69.4 N.A. N.A. 48.5 N.A. 48.7 N.A. 22.7 32 28.9 N.A.
Protein Similarity: 100 97.5 96 82.6 N.A. 81 79.1 N.A. N.A. 64 N.A. 64.2 N.A. 31.5 48.4 47.4 N.A.
P-Site Identity: 100 86.6 93.3 66.6 N.A. 26.6 33.3 N.A. N.A. 13.3 N.A. 20 N.A. 0 0 6.6 N.A.
P-Site Similarity: 100 93.3 100 86.6 N.A. 46.6 46.6 N.A. N.A. 46.6 N.A. 40 N.A. 6.6 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 23.5
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 0 31 0 0 16 8 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 0 16 31 47 0 8 16 0 0 0 47 8 0 % D
% Glu: 8 0 8 31 8 16 16 8 8 8 8 0 16 47 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 24 16 8 8 0 8 8 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 8 8 0 0 8 0 0 8 0 0 0 8 % I
% Lys: 54 8 16 0 0 0 16 8 0 0 8 0 0 0 8 % K
% Leu: 0 16 0 0 0 0 0 0 0 8 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 8 8 0 0 0 16 8 0 0 0 8 31 % N
% Pro: 0 0 31 0 0 8 0 8 31 0 8 24 0 8 0 % P
% Gln: 0 8 0 24 16 8 0 0 0 0 0 0 24 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 0 0 8 8 47 8 47 16 39 0 8 8 % S
% Thr: 0 47 8 0 0 0 0 8 8 0 39 8 0 0 8 % T
% Val: 0 8 8 0 0 0 8 0 8 8 0 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _