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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINX1
All Species:
11.82
Human Site:
S254
Identified Species:
21.67
UniProt:
Q96BK5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BK5
NP_060354.4
328
37035
S254
E
R
V
A
K
K
K
S
A
P
A
E
E
Q
L
Chimpanzee
Pan troglodytes
XP_519603
333
37605
S254
E
R
V
A
K
K
K
S
V
P
A
E
E
Q
L
Rhesus Macaque
Macaca mulatta
XP_001089816
328
36769
S253
Q
E
R
V
A
K
K
S
G
P
A
E
E
Q
L
Dog
Lupus familis
XP_849859
314
35718
D247
Q
V
E
W
Q
L
G
D
P
C
W
D
K
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX5
332
37202
R258
R
G
P
V
A
K
K
R
D
R
A
E
L
Q
P
Rat
Rattus norvegicus
A4L691
331
36692
R258
R
G
P
A
A
K
K
R
D
Q
V
E
L
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420036
356
40488
H278
D
A
P
L
D
E
C
H
S
R
K
K
K
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013283
355
40546
N280
K
K
K
K
S
R
R
N
E
E
D
E
V
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611495
726
82612
K446
K
R
K
S
D
K
N
K
E
I
A
E
D
S
I
Honey Bee
Apis mellifera
XP_391986
378
43625
N271
D
C
I
K
K
K
K
N
R
T
T
L
D
K
F
Nematode Worm
Caenorhab. elegans
NP_495955
339
39018
T265
E
Q
R
D
K
E
E
T
L
E
T
V
E
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53335
271
31293
L207
H
K
K
E
E
K
R
L
K
K
E
K
R
A
E
Red Bread Mold
Neurospora crassa
Q7SHT5
369
41722
S253
D
A
K
Q
S
E
E
S
S
S
D
D
L
E
S
Conservation
Percent
Protein Identity:
100
96.6
94.2
75.9
N.A.
72.8
69.4
N.A.
N.A.
48.5
N.A.
48.7
N.A.
22.7
32
28.9
N.A.
Protein Similarity:
100
97.5
96
82.6
N.A.
81
79.1
N.A.
N.A.
64
N.A.
64.2
N.A.
31.5
48.4
47.4
N.A.
P-Site Identity:
100
93.3
60
0
N.A.
33.3
33.3
N.A.
N.A.
0
N.A.
6.6
N.A.
26.6
20
20
N.A.
P-Site Similarity:
100
93.3
66.6
26.6
N.A.
33.3
33.3
N.A.
N.A.
40
N.A.
40
N.A.
53.3
53.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
23.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
40.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
24
24
0
0
0
8
0
39
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
24
0
0
8
16
0
0
8
16
0
16
16
16
0
0
% D
% Glu:
24
8
8
8
8
24
16
0
16
16
8
54
31
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
16
0
0
0
0
8
0
8
0
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
16
% I
% Lys:
16
16
31
16
31
62
47
8
8
8
8
16
16
8
8
% K
% Leu:
0
0
0
8
0
8
0
8
8
0
0
8
24
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
16
0
0
0
0
0
16
0
% N
% Pro:
0
0
24
0
0
0
0
0
8
24
0
0
0
0
16
% P
% Gln:
16
8
0
8
8
0
0
0
0
8
0
0
0
39
0
% Q
% Arg:
16
24
16
0
0
8
16
16
8
16
0
0
8
8
0
% R
% Ser:
0
0
0
8
16
0
0
31
16
8
0
0
0
8
16
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
16
0
0
8
0
% T
% Val:
0
8
16
16
0
0
0
0
8
0
8
8
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _