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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINX1 All Species: 35.15
Human Site: S27 Identified Species: 64.44
UniProt: Q96BK5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BK5 NP_060354.4 328 37035 S27 T A W S N D D S K F G Q R M L
Chimpanzee Pan troglodytes XP_519603 333 37605 S27 T A W S N D D S K F G Q R M L
Rhesus Macaque Macaca mulatta XP_001089816 328 36769 S27 T A W S N D D S K F G Q R M L
Dog Lupus familis XP_849859 314 35718 S27 T A W S N D D S K F G Q R M L
Cat Felis silvestris
Mouse Mus musculus Q9CZX5 332 37202 S27 T A W S N D D S K F G Q K M L
Rat Rattus norvegicus A4L691 331 36692 S27 T A W S N D D S K F G Q K M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420036 356 40488 S27 S A W S K D E S K F G Q R M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013283 355 40546 S27 S A W S N D E S K F G Q K M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611495 726 82612 N27 K A L Y E D E N R F G T K M L
Honey Bee Apis mellifera XP_391986 378 43625 N27 K E W S E D S N K F G Q K M L
Nematode Worm Caenorhab. elegans NP_495955 339 39018 Q27 L T W K N D D Q K L S K K L M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53335 271 31293
Red Bread Mold Neurospora crassa Q7SHT5 369 41722 T26 T K W S R N E T T F G Q K I L
Conservation
Percent
Protein Identity: 100 96.6 94.2 75.9 N.A. 72.8 69.4 N.A. N.A. 48.5 N.A. 48.7 N.A. 22.7 32 28.9 N.A.
Protein Similarity: 100 97.5 96 82.6 N.A. 81 79.1 N.A. N.A. 64 N.A. 64.2 N.A. 31.5 48.4 47.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 80 N.A. 80 N.A. 40 60 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 100 N.A. 66.6 73.3 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 23.5
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 0 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 0 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 85 54 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 16 0 31 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 16 8 0 8 8 0 0 0 77 0 0 8 54 0 0 % K
% Leu: 8 0 8 0 0 0 0 0 0 8 0 0 0 8 85 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 77 8 % M
% Asn: 0 0 0 0 62 8 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 77 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 8 0 0 0 39 0 0 % R
% Ser: 16 0 0 77 0 0 8 62 0 0 8 0 0 0 0 % S
% Thr: 54 8 0 0 0 0 0 8 8 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _