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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINX1
All Species:
17.88
Human Site:
S270
Identified Species:
32.78
UniProt:
Q96BK5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BK5
NP_060354.4
328
37035
S270
G
P
C
W
D
Q
S
S
K
A
S
A
Q
D
A
Chimpanzee
Pan troglodytes
XP_519603
333
37605
S270
G
P
C
W
D
Q
S
S
K
A
S
A
Q
D
A
Rhesus Macaque
Macaca mulatta
XP_001089816
328
36769
S269
G
P
C
W
D
R
S
S
E
A
S
A
P
D
A
Dog
Lupus familis
XP_849859
314
35718
D263
V
S
A
E
N
G
E
D
C
V
W
P
P
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX5
332
37202
S274
G
P
S
E
D
E
C
S
D
A
S
V
E
A
A
Rat
Rattus norvegicus
A4L691
331
36692
S274
G
P
S
G
D
E
C
S
D
A
S
V
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420036
356
40488
S294
K
E
Q
H
D
G
E
S
I
S
C
D
E
N
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013283
355
40546
E296
S
T
V
M
E
E
E
E
S
R
E
Q
V
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611495
726
82612
K462
E
P
A
A
K
K
K
K
K
S
K
K
S
D
E
Honey Bee
Apis mellifera
XP_391986
378
43625
K287
V
E
N
K
K
V
K
K
K
K
K
H
D
V
I
Nematode Worm
Caenorhab. elegans
NP_495955
339
39018
E281
E
V
K
Q
E
V
K
E
E
I
I
D
E
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53335
271
31293
S223
T
K
E
T
K
K
T
S
K
L
K
S
S
E
S
Red Bread Mold
Neurospora crassa
Q7SHT5
369
41722
K269
A
T
E
T
K
K
S
K
K
D
K
K
K
E
K
Conservation
Percent
Protein Identity:
100
96.6
94.2
75.9
N.A.
72.8
69.4
N.A.
N.A.
48.5
N.A.
48.7
N.A.
22.7
32
28.9
N.A.
Protein Similarity:
100
97.5
96
82.6
N.A.
81
79.1
N.A.
N.A.
64
N.A.
64.2
N.A.
31.5
48.4
47.4
N.A.
P-Site Identity:
100
100
80
0
N.A.
46.6
46.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
20
6.6
0
N.A.
P-Site Similarity:
100
100
93.3
6.6
N.A.
60
60
N.A.
N.A.
33.3
N.A.
26.6
N.A.
33.3
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
23.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
40.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
0
0
0
0
0
39
0
24
0
16
47
% A
% Cys:
0
0
24
0
0
0
16
0
8
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
8
16
8
0
16
8
31
0
% D
% Glu:
16
16
16
16
16
24
24
16
16
0
8
0
31
31
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
39
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% I
% Lys:
8
8
8
8
31
24
24
24
47
8
31
16
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
47
0
0
0
0
0
0
0
0
0
8
16
0
0
% P
% Gln:
0
0
8
8
0
16
0
0
0
0
0
8
16
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
16
0
0
0
31
54
8
16
39
8
16
0
8
% S
% Thr:
8
16
0
16
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
16
8
8
0
0
16
0
0
0
8
0
16
8
8
8
% V
% Trp:
0
0
0
24
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _