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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINX1
All Species:
13.64
Human Site:
S273
Identified Species:
25
UniProt:
Q96BK5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BK5
NP_060354.4
328
37035
S273
W
D
Q
S
S
K
A
S
A
Q
D
A
G
D
H
Chimpanzee
Pan troglodytes
XP_519603
333
37605
S273
W
D
Q
S
S
K
A
S
A
Q
D
A
G
D
H
Rhesus Macaque
Macaca mulatta
XP_001089816
328
36769
S272
W
D
R
S
S
E
A
S
A
P
D
A
G
D
H
Dog
Lupus familis
XP_849859
314
35718
W266
E
N
G
E
D
C
V
W
P
P
H
V
Q
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX5
332
37202
S277
E
D
E
C
S
D
A
S
V
E
A
A
E
D
C
Rat
Rattus norvegicus
A4L691
331
36692
S277
G
D
E
C
S
D
A
S
V
E
A
A
E
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420036
356
40488
C297
H
D
G
E
S
I
S
C
D
E
N
M
G
D
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013283
355
40546
E299
M
E
E
E
E
S
R
E
Q
V
E
A
D
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611495
726
82612
K465
A
K
K
K
K
K
S
K
K
S
D
E
V
I
V
Honey Bee
Apis mellifera
XP_391986
378
43625
K290
K
K
V
K
K
K
K
K
H
D
V
I
A
D
N
Nematode Worm
Caenorhab. elegans
NP_495955
339
39018
I284
Q
E
V
K
E
E
I
I
D
E
E
F
D
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53335
271
31293
K226
T
K
K
T
S
K
L
K
S
S
E
S
A
S
N
Red Bread Mold
Neurospora crassa
Q7SHT5
369
41722
K272
T
K
K
S
K
K
D
K
K
K
E
K
K
E
K
Conservation
Percent
Protein Identity:
100
96.6
94.2
75.9
N.A.
72.8
69.4
N.A.
N.A.
48.5
N.A.
48.7
N.A.
22.7
32
28.9
N.A.
Protein Similarity:
100
97.5
96
82.6
N.A.
81
79.1
N.A.
N.A.
64
N.A.
64.2
N.A.
31.5
48.4
47.4
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
40
40
N.A.
N.A.
26.6
N.A.
6.6
N.A.
13.3
13.3
0
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
53.3
53.3
N.A.
N.A.
46.6
N.A.
33.3
N.A.
26.6
20
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
23.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
40.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
39
0
24
0
16
47
16
0
8
% A
% Cys:
0
0
0
16
0
8
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
47
0
0
8
16
8
0
16
8
31
0
16
62
0
% D
% Glu:
16
16
24
24
16
16
0
8
0
31
31
8
16
24
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
16
0
0
0
0
0
0
0
0
0
31
0
8
% G
% His:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
24
% H
% Ile:
0
0
0
0
0
8
8
8
0
0
0
8
0
8
8
% I
% Lys:
8
31
24
24
24
47
8
31
16
8
0
8
8
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% P
% Gln:
8
0
16
0
0
0
0
0
8
16
0
0
8
0
8
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
31
54
8
16
39
8
16
0
8
0
8
0
% S
% Thr:
16
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
8
0
16
8
8
8
8
0
8
% V
% Trp:
24
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _