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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINX1
All Species:
17.58
Human Site:
T170
Identified Species:
32.22
UniProt:
Q96BK5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BK5
NP_060354.4
328
37035
T170
S
T
P
E
E
N
E
T
T
T
T
S
A
F
T
Chimpanzee
Pan troglodytes
XP_519603
333
37605
T170
S
T
S
D
E
N
E
T
T
T
T
S
A
F
T
Rhesus Macaque
Macaca mulatta
XP_001089816
328
36769
T170
S
T
P
D
E
N
E
T
T
T
T
S
A
F
T
Dog
Lupus familis
XP_849859
314
35718
S170
A
T
P
D
G
N
S
S
S
T
T
T
T
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX5
332
37202
T170
S
S
A
D
E
V
N
T
S
L
T
T
T
T
T
Rat
Rattus norvegicus
A4L691
331
36692
T170
S
T
A
D
E
A
D
T
S
L
T
T
T
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420036
356
40488
H170
A
E
S
Q
E
E
K
H
G
G
C
W
L
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013283
355
40546
D168
S
G
S
D
S
Q
E
D
K
E
D
S
E
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611495
726
82612
P194
L
A
V
Q
P
E
E
P
N
P
N
F
A
G
V
Honey Bee
Apis mellifera
XP_391986
378
43625
E171
N
S
S
V
G
I
Q
E
N
R
N
G
V
I
T
Nematode Worm
Caenorhab. elegans
NP_495955
339
39018
V174
E
K
T
E
N
S
S
V
K
S
D
S
S
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53335
271
31293
E130
G
I
H
F
V
K
G
E
V
L
A
S
T
W
D
Red Bread Mold
Neurospora crassa
Q7SHT5
369
41722
D171
V
P
S
Q
D
T
K
D
A
E
P
T
K
R
K
Conservation
Percent
Protein Identity:
100
96.6
94.2
75.9
N.A.
72.8
69.4
N.A.
N.A.
48.5
N.A.
48.7
N.A.
22.7
32
28.9
N.A.
Protein Similarity:
100
97.5
96
82.6
N.A.
81
79.1
N.A.
N.A.
64
N.A.
64.2
N.A.
31.5
48.4
47.4
N.A.
P-Site Identity:
100
86.6
93.3
33.3
N.A.
33.3
40
N.A.
N.A.
6.6
N.A.
20
N.A.
13.3
6.6
13.3
N.A.
P-Site Similarity:
100
93.3
100
66.6
N.A.
60
66.6
N.A.
N.A.
26.6
N.A.
26.6
N.A.
20
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
23.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
40.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
16
0
0
8
0
0
8
0
8
0
31
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
47
8
0
8
16
0
0
16
0
0
8
8
% D
% Glu:
8
8
0
16
47
16
39
16
0
16
0
0
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
24
0
% F
% Gly:
8
8
0
0
16
0
8
0
8
8
0
8
0
8
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
8
16
0
16
0
0
0
8
0
8
% K
% Leu:
8
0
0
0
0
0
0
0
0
24
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
31
8
0
16
0
16
0
0
0
0
% N
% Pro:
0
8
24
0
8
0
0
8
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
24
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
47
16
39
0
8
8
16
8
24
8
0
47
8
8
8
% S
% Thr:
0
39
8
0
0
8
0
39
24
31
47
31
31
24
47
% T
% Val:
8
0
8
8
8
8
0
8
8
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _