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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINX1 All Species: 21.82
Human Site: T205 Identified Species: 40
UniProt: Q96BK5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BK5 NP_060354.4 328 37035 T205 P G S D I S E T Q V E R K R G
Chimpanzee Pan troglodytes XP_519603 333 37605 T205 P G S D I S E T Q V E R K R G
Rhesus Macaque Macaca mulatta XP_001089816 328 36769 T205 P G S D T S K T Q V E H K R G
Dog Lupus familis XP_849859 314 35718 G201 K P Q V I A A G P D F A E T Q
Cat Felis silvestris
Mouse Mus musculus Q9CZX5 332 37202 T211 P G S D L S E T P V E R K K G
Rat Rattus norvegicus A4L691 331 36692 T211 P G S D L S E T P I E W K K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420036 356 40488 T232 E L S E E L K T K A K K K K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013283 355 40546 K233 S D A E Q T K K K R K K K K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611495 726 82612 E255 Q I S A D N D E V T S K K K K
Honey Bee Apis mellifera XP_391986 378 43625 Y214 K N K E E S E Y P G F G F S S
Nematode Worm Caenorhab. elegans NP_495955 339 39018 A206 S V G D Y F A A K M A A L K A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53335 271 31293 D161 R E G D D S E D E D D D D K E
Red Bread Mold Neurospora crassa Q7SHT5 369 41722 T207 V K K R K T D T E A E T D S E
Conservation
Percent
Protein Identity: 100 96.6 94.2 75.9 N.A. 72.8 69.4 N.A. N.A. 48.5 N.A. 48.7 N.A. 22.7 32 28.9 N.A.
Protein Similarity: 100 97.5 96 82.6 N.A. 81 79.1 N.A. N.A. 64 N.A. 64.2 N.A. 31.5 48.4 47.4 N.A.
P-Site Identity: 100 100 80 6.6 N.A. 80 66.6 N.A. N.A. 20 N.A. 6.6 N.A. 13.3 13.3 6.6 N.A.
P-Site Similarity: 100 100 86.6 20 N.A. 93.3 86.6 N.A. N.A. 60 N.A. 60 N.A. 40 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 23.5
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 16 8 0 16 8 16 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 54 16 0 16 8 0 16 8 8 16 0 8 % D
% Glu: 8 8 0 24 16 0 47 8 16 0 47 0 8 0 16 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 16 0 8 0 0 % F
% Gly: 0 39 16 0 0 0 0 8 0 8 0 8 0 0 39 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 24 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 16 8 16 0 8 0 24 8 24 0 16 24 62 54 16 % K
% Leu: 0 8 0 0 16 8 0 0 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 39 8 0 0 0 0 0 0 31 0 0 0 0 0 0 % P
% Gln: 8 0 8 0 8 0 0 0 24 0 0 0 0 0 8 % Q
% Arg: 8 0 0 8 0 0 0 0 0 8 0 24 0 24 0 % R
% Ser: 16 0 54 0 0 54 0 0 0 0 8 0 0 16 8 % S
% Thr: 0 0 0 0 8 16 0 54 0 8 0 8 0 8 0 % T
% Val: 8 8 0 8 0 0 0 0 8 31 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _