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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PINX1 All Species: 7.88
Human Site: T236 Identified Species: 14.44
UniProt: Q96BK5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BK5 NP_060354.4 328 37035 T236 Q P K A K R H T E G K P E R A
Chimpanzee Pan troglodytes XP_519603 333 37605 T236 Q P K A K R H T E G K P E R A
Rhesus Macaque Macaca mulatta XP_001089816 328 36769 M236 Q P K A K R D M E G K P E R A
Dog Lupus familis XP_849859 314 35718 P232 K V E T Y T V P K A K K K R H
Cat Felis silvestris
Mouse Mus musculus Q9CZX5 332 37202 K242 Q H K A K R H K K K K R V E A
Rat Rattus norvegicus A4L691 331 36692 K242 Q H K A K R H K K K K R V E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420036 356 40488 S263 Q G K K C K I S S L N G K E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001013283 355 40546 P264 T G E S V E E P Q N H S Q K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611495 726 82612 M286 E P E Q V A S M P K K K K K S
Honey Bee Apis mellifera XP_391986 378 43625 S245 Q T D S L D L S D E V N K K R
Nematode Worm Caenorhab. elegans NP_495955 339 39018 E237 K T E V E E E E S D E E K A R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53335 271 31293 K192 K D K K K D K K D K K E H K K
Red Bread Mold Neurospora crassa Q7SHT5 369 41722 K238 D Q K E K K D K K D K R K L K
Conservation
Percent
Protein Identity: 100 96.6 94.2 75.9 N.A. 72.8 69.4 N.A. N.A. 48.5 N.A. 48.7 N.A. 22.7 32 28.9 N.A.
Protein Similarity: 100 97.5 96 82.6 N.A. 81 79.1 N.A. N.A. 64 N.A. 64.2 N.A. 31.5 48.4 47.4 N.A.
P-Site Identity: 100 100 86.6 13.3 N.A. 53.3 53.3 N.A. N.A. 13.3 N.A. 0 N.A. 13.3 6.6 0 N.A.
P-Site Similarity: 100 100 86.6 40 N.A. 60 60 N.A. N.A. 33.3 N.A. 33.3 N.A. 46.6 40 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 23.5
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 20 20
P-Site Similarity: N.A. N.A. N.A. N.A. 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 39 0 8 0 0 0 8 0 0 0 8 39 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 16 16 0 16 16 0 0 0 0 0 % D
% Glu: 8 0 31 8 8 16 16 8 24 8 8 16 24 24 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 16 0 0 0 0 0 0 0 24 0 8 0 0 0 % G
% His: 0 16 0 0 0 0 31 0 0 0 8 0 8 0 8 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 24 0 62 16 54 16 8 31 31 31 70 16 47 31 24 % K
% Leu: 0 0 0 0 8 0 8 0 0 8 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % N
% Pro: 0 31 0 0 0 0 0 16 8 0 0 24 0 0 0 % P
% Gln: 54 8 0 8 0 0 0 0 8 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 39 0 0 0 0 0 24 0 31 16 % R
% Ser: 0 0 0 16 0 0 8 16 16 0 0 8 0 0 8 % S
% Thr: 8 16 0 8 0 8 0 16 0 0 0 0 0 0 0 % T
% Val: 0 8 0 8 16 0 8 0 0 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _