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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PINX1
All Species:
13.64
Human Site:
T290
Identified Species:
25
UniProt:
Q96BK5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BK5
NP_060354.4
328
37035
T290
P
P
E
G
R
D
F
T
L
K
P
K
K
R
R
Chimpanzee
Pan troglodytes
XP_519603
333
37605
T290
P
P
E
G
Q
D
F
T
L
K
P
K
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001089816
328
36769
T289
P
P
E
G
G
D
F
T
L
K
P
K
K
R
R
Dog
Lupus familis
XP_849859
314
35718
R281
T
L
K
S
K
K
R
R
E
K
K
K
L
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZX5
332
37202
V294
T
P
D
I
Q
D
D
V
P
K
P
K
K
R
K
Rat
Rattus norvegicus
A4L691
331
36692
V294
T
P
D
T
Q
D
D
V
P
K
P
R
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420036
356
40488
S317
V
S
D
G
E
D
L
S
V
E
D
S
E
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013283
355
40546
K317
E
I
E
N
Q
D
S
K
V
S
E
K
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611495
726
82612
S527
P
S
K
K
K
K
K
S
K
E
E
K
R
K
D
Honey Bee
Apis mellifera
XP_391986
378
43625
E321
I
E
E
V
H
D
N
E
V
N
E
R
K
S
K
Nematode Worm
Caenorhab. elegans
NP_495955
339
39018
L303
L
K
K
E
K
K
R
L
K
R
L
R
E
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53335
271
31293
R241
I
P
D
A
V
N
T
R
L
S
V
R
S
K
W
Red Bread Mold
Neurospora crassa
Q7SHT5
369
41722
K287
K
D
K
K
K
D
K
K
E
K
K
R
K
E
K
Conservation
Percent
Protein Identity:
100
96.6
94.2
75.9
N.A.
72.8
69.4
N.A.
N.A.
48.5
N.A.
48.7
N.A.
22.7
32
28.9
N.A.
Protein Similarity:
100
97.5
96
82.6
N.A.
81
79.1
N.A.
N.A.
64
N.A.
64.2
N.A.
31.5
48.4
47.4
N.A.
P-Site Identity:
100
93.3
93.3
13.3
N.A.
46.6
46.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
13.3
20
0
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
66.6
66.6
N.A.
N.A.
53.3
N.A.
53.3
N.A.
53.3
40
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
23.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
40.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
31
0
0
70
16
0
0
0
8
0
0
0
8
% D
% Glu:
8
8
39
8
8
0
0
8
16
16
24
0
16
8
0
% E
% Phe:
0
0
0
0
0
0
24
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
31
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
31
16
31
24
16
16
16
54
16
54
62
24
39
% K
% Leu:
8
8
0
0
0
0
8
8
31
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
8
0
0
8
0
0
0
0
8
% N
% Pro:
31
47
0
0
0
0
0
0
16
0
39
0
0
0
0
% P
% Gln:
0
0
0
0
31
0
0
0
0
0
0
0
0
16
8
% Q
% Arg:
0
0
0
0
8
0
16
16
0
8
0
39
8
39
31
% R
% Ser:
0
16
0
8
0
0
8
16
0
16
0
8
8
8
0
% S
% Thr:
24
0
0
8
0
0
8
24
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
8
0
0
16
24
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _