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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPWD1 All Species: 23.64
Human Site: S28 Identified Species: 40
UniProt: Q96BP3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BP3 NP_056157.1 646 73575 S28 E P E K T E L S E R E L A V A
Chimpanzee Pan troglodytes XP_001164190 646 73612 S28 E P E K T E L S E R E L A V A
Rhesus Macaque Macaca mulatta XP_001085845 646 73558 S28 E S E K T E L S E R E L A V A
Dog Lupus familis XP_535256 646 73593 S28 E P E K T E R S E R E L T V V
Cat Felis silvestris
Mouse Mus musculus Q8CEC6 646 73412 S28 G S E K T E L S E R E P A L A
Rat Rattus norvegicus NP_001099876 646 73476 S28 G S E K T E L S E R E P A L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424751 625 70981 E27 E E D E E D G E R W V G P L P
Frog Xenopus laevis NP_001091218 642 72464 S26 S S S S S S S S E D E V P E K
Zebra Danio Brachydanio rerio NP_001092228 622 70606 V26 D E D E E N W V G P M P S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611935 637 71743 S26 E P Q E E S V S S E K E A E G
Honey Bee Apis mellifera XP_396986 612 69983 K29 P S E A V P Q K K Q K V L E Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177287 619 70117 I25 E E E D E E W I G P M P A E A
Poplar Tree Populus trichocarpa XP_002312902 620 69816 A41 R P L Q F E Q A Y L D S L P S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_190046 631 70965 V25 A V V A V P P V V E E E E P M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.3 97.2 N.A. 96.4 96.5 N.A. N.A. 89.3 84.3 81.5 N.A. 58.6 63.6 N.A. 63.7
Protein Similarity: 100 100 99.8 98.6 N.A. 97.9 97.9 N.A. N.A. 93 90.4 89.3 N.A. 76.6 77.7 N.A. 78.9
P-Site Identity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. N.A. 6.6 20 6.6 N.A. 26.6 6.6 N.A. 33.3
P-Site Similarity: 100 100 93.3 80 N.A. 80 80 N.A. N.A. 33.3 33.3 33.3 N.A. 53.3 33.3 N.A. 33.3
Percent
Protein Identity: 50.1 N.A. N.A. 50.9 N.A. N.A.
Protein Similarity: 68.4 N.A. N.A. 69.2 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 0 0 8 0 0 0 0 50 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 15 8 0 8 0 0 0 8 8 0 0 0 0 % D
% Glu: 50 22 58 22 29 58 0 8 50 15 58 15 8 36 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 0 0 0 8 0 15 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 43 0 0 0 8 8 0 15 0 0 0 8 % K
% Leu: 0 0 8 0 0 0 36 0 0 8 0 29 15 22 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 8 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 36 0 0 0 15 8 0 0 15 0 29 15 15 8 % P
% Gln: 0 0 8 8 0 0 15 0 0 8 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 8 0 8 43 0 0 0 0 0 % R
% Ser: 8 36 8 8 8 15 8 58 8 0 0 8 8 0 8 % S
% Thr: 0 0 0 0 43 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 8 8 0 15 0 8 15 8 0 8 15 0 29 8 % V
% Trp: 0 0 0 0 0 0 15 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _