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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPWD1
All Species:
41.21
Human Site:
T459
Identified Species:
69.74
UniProt:
Q96BP3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96BP3
NP_056157.1
646
73575
T459
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Chimpanzee
Pan troglodytes
XP_001164190
646
73612
T459
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Rhesus Macaque
Macaca mulatta
XP_001085845
646
73558
T459
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Dog
Lupus familis
XP_535256
646
73593
T459
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEC6
646
73412
T459
T
K
R
E
T
E
D
T
K
T
A
D
S
D
R
Rat
Rattus norvegicus
NP_001099876
646
73476
T459
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424751
625
70981
T438
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Frog
Xenopus laevis
NP_001091218
642
72464
T455
T
K
R
E
P
E
D
T
K
S
A
E
S
D
R
Zebra Danio
Brachydanio rerio
NP_001092228
622
70606
T435
T
K
R
E
P
E
D
T
K
S
A
D
S
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611935
637
71743
S449
L
Y
S
R
R
L
P
S
D
L
Q
D
V
D
R
Honey Bee
Apis mellifera
XP_396986
612
69983
T425
T
R
R
E
P
E
D
T
K
S
Q
E
C
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177287
619
70117
A433
T
R
R
E
P
D
D
A
K
S
N
E
A
E
R
Poplar Tree
Populus trichocarpa
XP_002312902
620
69816
D432
R
E
P
E
E
P
E
D
A
T
K
G
R
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_190046
631
70965
D443
R
E
P
E
E
P
E
D
A
S
Q
G
R
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.3
97.2
N.A.
96.4
96.5
N.A.
N.A.
89.3
84.3
81.5
N.A.
58.6
63.6
N.A.
63.7
Protein Similarity:
100
100
99.8
98.6
N.A.
97.9
97.9
N.A.
N.A.
93
90.4
89.3
N.A.
76.6
77.7
N.A.
78.9
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
100
93.3
100
N.A.
20
73.3
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
100
100
100
N.A.
26.6
86.6
N.A.
86.6
Percent
Protein Identity:
50.1
N.A.
N.A.
50.9
N.A.
N.A.
Protein Similarity:
68.4
N.A.
N.A.
69.2
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
15
0
65
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
8
79
15
8
0
0
65
0
93
0
% D
% Glu:
0
15
0
93
15
72
15
0
0
0
0
22
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
65
0
0
0
0
0
0
79
0
8
0
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
15
0
72
15
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
22
0
0
0
0
% Q
% Arg:
15
15
79
8
8
0
0
0
0
0
0
0
15
0
86
% R
% Ser:
0
0
8
0
0
0
0
8
0
79
0
0
65
0
0
% S
% Thr:
79
0
0
0
8
0
0
72
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _