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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGK3 All Species: 28.79
Human Site: S421 Identified Species: 48.72
UniProt: Q96BR1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BR1 NP_001028750.1 496 57108 S421 Q N H P F F E S L S W A D L V
Chimpanzee Pan troglodytes XP_001161460 496 57046 S421 Q N H P F F E S L S W A D L V
Rhesus Macaque Macaca mulatta XP_001102277 637 72261 L563 K S H V F F S L I N W D D L I
Dog Lupus familis XP_544110 490 56348 S415 Q N H P F F E S L S W T D L V
Cat Felis silvestris
Mouse Mus musculus Q9ERE3 496 57127 S421 Q N H P F F E S L S W T D L V
Rat Rattus norvegicus Q8R4V0 496 57153 S421 Q N H P F F E S L S W T D L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512995 490 56401 S415 Q N H P F F E S L S W T D L V
Chicken Gallus gallus Q6U1I9 432 48872 P358 K N H I F F S P I N W D D L I
Frog Xenopus laevis Q6GLY8 434 49082 P360 K N H I F F S P I D W D D L I
Zebra Danio Brachydanio rerio Q7ZTW4 433 48964 D364 F S P I N W D D L N A K K L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INB9 611 68466 S525 Q A H P F F A S I N W T D L V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q2PJ68 463 54273 P394 R D H P F F L P V D W D K L L
Sea Urchin Strong. purpuratus XP_001192139 440 49530 S364 K H H E F F S S I S W S D L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P18961 677 76646 D601 R N H P F F K D I S W K K L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 48 97.5 N.A. 96.7 96.5 N.A. 94.9 58.8 56.4 59 N.A. 34.7 N.A. 44.5 56.6
Protein Similarity: 100 99.8 59.8 98.3 N.A. 98.3 98.3 N.A. 96.7 70.3 69.3 70.5 N.A. 48.6 N.A. 59.6 68.7
P-Site Identity: 100 100 40 93.3 N.A. 93.3 93.3 N.A. 93.3 46.6 46.6 13.3 N.A. 66.6 N.A. 40 53.3
P-Site Similarity: 100 100 73.3 93.3 N.A. 93.3 93.3 N.A. 93.3 73.3 66.6 40 N.A. 80 N.A. 66.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 0 0 0 8 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 15 0 15 0 29 79 0 8 % D
% Glu: 0 0 0 8 0 0 43 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 93 93 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 93 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 22 0 0 0 0 43 0 0 0 0 0 22 % I
% Lys: 29 0 0 0 0 0 8 0 0 0 0 15 22 0 0 % K
% Leu: 0 0 0 0 0 0 8 8 50 0 0 0 0 100 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 65 0 0 8 0 0 0 0 29 0 0 0 0 0 % N
% Pro: 0 0 8 65 0 0 0 22 0 0 0 0 0 0 0 % P
% Gln: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 0 0 0 0 29 58 0 58 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 36 0 0 8 % T
% Val: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 93 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _