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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALKBH8 All Species: 20.61
Human Site: S206 Identified Species: 37.78
UniProt: Q96BT7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BT7 NP_620130.2 664 75208 S206 G L P D I C E S F L E K W L R
Chimpanzee Pan troglodytes XP_522172 664 75155 S206 G L P D I C D S F L E K W L R
Rhesus Macaque Macaca mulatta XP_001102763 664 75113 S206 G L P D I C D S F L E K W L R
Dog Lupus familis XP_546542 661 74257 S206 G L P G I C D S F L E K W L K
Cat Felis silvestris
Mouse Mus musculus Q80Y20 664 74749 S206 G L P E V C S S I L E K L L K
Rat Rattus norvegicus XP_001055538 664 74826 S206 G L P E I C S S I L E K L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508849 715 79108 G257 G L P E M C G G V L E R C L K
Chicken Gallus gallus XP_417166 679 76991 P214 G L P E I C I P F L E K C L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684243 693 77051 A230 G L P V E C D A L L Q R C L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611690 615 69276 A201 L E Q S I P S A C D I L W P R
Honey Bee Apis mellifera XP_395117 558 65352 Q144 K H F G Y E F Q Y D T N K V D
Nematode Worm Caenorhab. elegans NP_497751 591 67352 F177 K H R A V V H F G H V F D Y S
Sea Urchin Strong. purpuratus XP_797576 424 47124 V10 S S G G A E A V A D S P T K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 96.9 82.6 N.A. 77.2 76.8 N.A. 66.4 66.2 N.A. 55.5 N.A. 42.3 40.9 35.6 32.9
Protein Similarity: 100 99 98.4 90.3 N.A. 85.5 84.9 N.A. 77.6 80.8 N.A. 71 N.A. 57.6 57.2 54.2 45.1
P-Site Identity: 100 93.3 93.3 80 N.A. 60 66.6 N.A. 46.6 66.6 N.A. 40 N.A. 20 0 0 0
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 73.3 80 N.A. 66.6 N.A. 26.6 13.3 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 16 8 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 70 0 0 8 0 0 0 24 0 0 % C
% Asp: 0 0 0 24 0 0 31 0 0 24 0 0 8 0 8 % D
% Glu: 0 8 0 31 8 16 8 0 0 0 62 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 8 8 39 0 0 8 0 0 0 % F
% Gly: 70 0 8 24 0 0 8 8 8 0 0 0 0 0 0 % G
% His: 0 16 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 54 0 8 0 16 0 8 0 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 0 0 0 0 54 8 8 39 % K
% Leu: 8 70 0 0 0 0 0 0 8 70 0 8 16 70 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 70 0 0 8 0 8 0 0 0 8 0 8 0 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 16 0 0 31 % R
% Ser: 8 8 0 8 0 0 24 47 0 0 8 0 0 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 0 0 0 8 16 8 0 8 8 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 8 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _