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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALKBH8 All Species: 20.61
Human Site: S351 Identified Species: 37.78
UniProt: Q96BT7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96BT7 NP_620130.2 664 75208 S351 S Y P L V C D S Q R K E T P P
Chimpanzee Pan troglodytes XP_522172 664 75155 S351 S Y P L V C D S Q R K E T P P
Rhesus Macaque Macaca mulatta XP_001102763 664 75113 S351 S Y P L V C D S Q R K E T P P
Dog Lupus familis XP_546542 661 74257 S351 S Y P L V C D S Q M K E T P P
Cat Felis silvestris
Mouse Mus musculus Q80Y20 664 74749 R351 S Y S S V C D R Q R K A T P P
Rat Rattus norvegicus XP_001055538 664 74826 R351 S Y S S V C D R Q R K A T P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508849 715 79108 D405 S V C D S Q G D Q P R E A S P
Chicken Gallus gallus XP_417166 679 76991 G363 S V C D S Q K G Q Q R Q A E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684243 693 77051 S375 A Y P S V C D S Q R P P S P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611690 615 69276 T339 S Y P A L C D T Q Q T K V P Q
Honey Bee Apis mellifera XP_395117 558 65352 V282 V S F T F R K V H R G D C C C
Nematode Worm Caenorhab. elegans NP_497751 591 67352 S315 V P R Q T R V S L T L R K I R
Sea Urchin Strong. purpuratus XP_797576 424 47124 P148 P P G L V I I P D F I D E C L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 96.9 82.6 N.A. 77.2 76.8 N.A. 66.4 66.2 N.A. 55.5 N.A. 42.3 40.9 35.6 32.9
Protein Similarity: 100 99 98.4 90.3 N.A. 85.5 84.9 N.A. 77.6 80.8 N.A. 71 N.A. 57.6 57.2 54.2 45.1
P-Site Identity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 26.6 20 N.A. 66.6 N.A. 46.6 6.6 6.6 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 33.3 40 N.A. 80 N.A. 73.3 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 0 0 0 0 0 16 16 0 0 % A
% Cys: 0 0 16 0 0 62 0 0 0 0 0 0 8 16 8 % C
% Asp: 0 0 0 16 0 0 62 8 8 0 0 16 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 39 8 8 0 % E
% Phe: 0 0 8 0 8 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 8 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 8 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 16 0 0 0 47 8 8 0 0 % K
% Leu: 0 0 0 39 8 0 0 0 8 0 8 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 16 47 0 0 0 0 8 0 8 8 8 0 62 70 % P
% Gln: 0 0 0 8 0 16 0 0 77 16 0 8 0 0 8 % Q
% Arg: 0 0 8 0 0 16 0 16 0 54 16 8 0 0 8 % R
% Ser: 70 8 16 24 16 0 0 47 0 0 0 0 8 8 0 % S
% Thr: 0 0 0 8 8 0 0 8 0 8 8 0 47 0 0 % T
% Val: 16 16 0 0 62 0 8 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _